Innovative optimization of greater omentum imaging report and data system for enhanced risk stratification of omental lesions.

Background: In 2020, we introduced the Greater Omentum Imaging-Reporting and Data System (GOI-RADS), a novel classification system related to peritoneal lesions. However, its clinical application remained unvalidated.

Objective: This study aimed to validate GOI-RADS, optimize its parameters for a new grading system, and explore its clinical usefulness.

Sono-Piezo Dynamic Therapy: Utilizing Piezoelectric Materials as Sonosensitizer for Sonodynamic Therapy.

Sonodynamic therapy (SDT) represents a promising approach for cancer treatment. Compared to photodynamic therapy, SDT offers increased penetration depth and higher precision. However, the practical application of SDT is constrained by the low water solubility, poor tumor specificity, and metabolic susceptibility of most sonosensitizers.

Low-intensity ultrasound combined with arsenic trioxide induced apoptosis of glioma via EGFR/AKT/mTOR.

Aims: This study aimed to explore whether low-intensity ultrasound (LIUS) combined with low-concentration arsenic trioxide (ATO) could inhibit the proliferation of glioma and, if so, to clarify the potential mechanism.

Main Methods: The effects of ATO and LIUS alone or in combination on glioma were examined by CCK8, EdU, and flow cytometry assays. Western blot analysis was used to detect changes in expression of apoptosis-related proteins and their effects on the EGFR/AKT/mTOR pathway.

Hydrogen production by traditional and novel alkaline water electrolysis on nickel or iron based electrocatalysts.

Hydrogen production through alkaline water electrolysis holds great promise as a scalable solution for renewable energy storage and conversion. The development of non-precious metal-based electrocatalysts with low-overpotential for alkaline water electrolysis is essential to decrease the cost of electrolysis devices. Although the Ni-based and Fe-based electrocatalysts have been commercially employed in the cathodic hydrogen evolution reaction (HER) and anodic oxygen evolution reaction (OER), it is imperative to persistently pursue the advancement of highly efficient electrocatalysts with enhanced current density and fast kinetics.

Pharyngoesophageal diverticulum mimicking thyroid nodules: Some interesting ultrasonographic signs.

Objective: To analyze the ultrasonographic features of pharyngoesophageal diverticulum (PED) mimicking thyroid nodules and to explore the clinical value of ultrasonography in the diagnosis of PED.

Method: The sonographic findings of 68 patients with PED were retrospectively reviewed. According to the diverticulum echo intensity characteristics, the lesions were divided into solid nodular diverticulum, gas-containing nodular diverticulum, liquid-containing nodular diverticulum, and atypical diverticular changes; and the ultrasonographic manifestations were compared among the four groups.

Low-intensity ultrasound: A novel technique for adjuvant treatment of gliomas.

Glioma is the most common primary malignant tumor of the central nervous system. Although surgical treatment combined with radiotherapy, chemotherapy, and immunotherapy are commonly used for glioma treatment, the prognosis of glioma is still unsatisfactory. The poor effect of glioma treatment could be due to the blocking effect of blood-brain barrier (BBB) on most drugs and the multidrug resistance in tumor cells.

Establishment and Validation of a 5 m6A RNA Methylation Regulatory Gene Prognostic Model in Low-Grade Glioma.

The prognosis of low-grade glioma (LGG) is different from that of other intracranial tumors. Although many markers of LGG have been established, few are used in clinical practice. M6A methylation significantly affects the biological behavior of LGG tumors.

Long Noncoding RNA LIFR-AS1: A New Player in Human Cancers.

Emerging evidence has indicated that aberrantly expressed long noncoding RNAs (lncRNAs) play a vital role in various biological processes associated with tumorigenesis. Leukemia inhibitory factor receptor antisense RNA1 (LIFR-AS1) is a recently identified lncRNA transcribed in an antisense manner from the gene located on human chromosome 5p13.1.

Highly efficient hamburger-like nanostructure of a triadic Ag/CoO/BiVO photoanode for enhanced photoelectrochemical water oxidation.

The combination of a semiconductor heterojunction and oxygen evolution cocatalyst (OEC) is an important strategy to improve photoelectrochemical (PEC) water oxidation. Herein, a novel hamburger-like nanostructure of a triadic photoanode composed of BiVO nanobulks, CoO nanosheets and Ag nanoparticles (NPs), that is, Ag/CoO/BiVO, was designed. In our study, an interlaced 2D ultrathin p-type CoO OEC layer was introduced onto n-type BiVO to form a p-n CoO/BiVO heterojunction with an internal electric field (IEF) in order to facilitate charge transport.

Curcumin combined with low-intensity ultrasound suppresses the growth of glioma cells via inhibition of the AKT pathway.

Malignant glioma is the most lethal form of brain cancer, and effective therapeutic modalities remain unavailable to date. We aim to investigate whether low-dose curcumin combined with low-intensity ultrasound (LIUS) effectively suppresses the growth of glioma cells and elucidate the underlying mechanisms. Glioma cells were treated with LIUS and curcumin.

Diagnostic Accuracy of Contrast-Enhanced Ultrasonography in Papillary Thyroid Microcarcinoma Stratified by Size.

We explored the diagnostic accuracy of ultrasonography (US) in papillary thyroid microcarcinoma (PTMC), studying nodular growths according to size via 3-D color Doppler US (3-DCDUS) and contrast-enhanced US (CEUS). A total of 109 patients undergoing CEUS and surgery of thyroid nodules at the First Hospital of China Medical University between January 2017 and December 2018 were selected for the study, including 77 with post-operative pathologically confirmed PTMC (test group) and 32 with nodular goiter (controls). All nodules were ≤1.