Improving the capturing ability of swirl-based microfluidic chip by introducing baffle wall.

Microfluidics technology is promising in developing microparticle manipulation technology due to its nondestructive control and notable adaptability. The manipulation of microparticle based on swirling stagnation point is one of the feasible microfluidics biotechnologies. Aiming to improve the regulation and control of microparticle, baffle wall is introduced into the 2-microchannel flow field.

Particle sorting method based on swirl induction.

Fluid-based methods for particle sorting demonstrate increasing appeal in many areas of biosciences due to their biocompatibility and cost-effectiveness. Herein, we construct a microfluidic sorting system based on a swirl microchip. The impact of microchannel velocity on the swirl stagnation point as well as particle movement is analyzed through simulation and experiment.

Microparticle Manipulation Performed on a Swirl-Based Microfluidic Chip Featured by Dual-Stagnation Points.

Stagnation-based microfluidics technology is promising for microparticle control due to its noncontact and low cost. However, the current research is still hindered by insufficient pose regulating ability and soft control. Based on our previous work on controlling single particles by generating a swirling flow region (SFR) with a stagnation point in the designed flow field, a new 3-microchannel structure is herein proposed for simultaneous control of two microparticles.