g-CN S-Scheme Homojunction through Van der Waals Interface Regulation by Intrinsic Polymerization Tailoring for Enhanced Photocatalytic H Evolution and CO Reduction.

The effective S-scheme homojunction relies on the precise regulation of band structure and construction of advantaged charge migration interfaces. Here, the electronic structural properties of g-CN were modulated through meticulous polymerization of self-assembled supramolecular precursors. Experimental and DFT results indicate that both the intrinsic bandgap and surface electronic characteristics were adjusted, leading to the formation of an in-situ reconstructed homojunction interface facilitated by intrinsic van der Waals forces.

Establishment and verification of reference intervals for blood cell analysis in extremely high altitude.

Objective: This study aimed to establish the reference intervals for complete blood count (CBC) in healthy adults at very high altitudes.

Methods: This study recruited 4,863 healthy adults (3,598 males and 1,265 females) who received routine health check-ups at Ali District People's Hospital from January 2019 to December 2021 through the LIS system. CBC was detected by the XT-4000i automatic cell analyzer and statistically analyzed by SPSS 23.

Association between tooth loss and depression mediated by lifestyle and Inflammation- a cross-sectional investigation.

Background: Depression and tooth loss are associated with the occurrence of systemic disease or the progression of multi-factorial disease, and both are considered important public health issues by World Health Organization (WHO). Previous research just suggested that tooth loss can generate psychological stress, low self-esteem, anxiety and other emotional disturbances. However, the precise correlation and underlying mechanisms between depression and tooth loss remains poorly understood.

Applications of Ni-Based Catalysts in Photothermal CO Hydrogenation Reaction.

Heterogeneous CO hydrogenation catalytic reactions, as the strategies for CO emission reduction and green carbon resource recycling, play important roles in alleviating global warming and energy shortages. Among these strategies, photothermal CO hydrogenation technology has become one of the hot catalytic technologies by virtue of the synergistic advantages of thermal catalysis and photocatalysis. And it has attracted more and more researchers' attentions.

Effectiveness of Global Leadership Initiative on Malnutrition and Subjective Global Assessment for diagnosing malnutrition and predicting wound healing in patients with diabetic foot ulcers.

Malnutrition significantly hampers wound healing processes. This study aimed to compare the effectiveness of the Global Leadership Initiative on Malnutrition (GLIM) and Subjective Global Assessment (SGA) in diagnosing malnutrition and predicting wound healing in patients with diabetic foot ulcers (DFU). GLIM criteria were evaluated for sensitivity (SE), specificity (SP), positive predictive value, negative predictive value and kappa (κ) against SGA as the reference.

Constructing extrinsic oxygen vacancy on the surface of photocatalyst as CO and electrons reservoirs to improve photocatalytic CO reduction activity.

Constructing own oxygen vacancies in the photocatalysts is a very promising method to improve their photocatalytic CO reduction activity. However, some catalysts have excellent stabilities, making it difficult for them to construct their own oxygen vacancies. To simplify the above difficulty of stable photocatalysts, constructing extrinsic oxygen vacancies on their surface as a novel idea is proposed.

Acellular embryoid body and hydroxybutyl chitosan composite hydrogels promote M2 macrophage polarization and accelerate diabetic cutaneous wound healing.

Diabetic wound healing is delayed due to persistent inflammation, and macrophage-immunomodulating biomaterials can control the inflammatory phase and shorten the healing time. In this study, acellular embryoid bodies (aEBs) were prepared and mixed with thermosensitive hydroxybutyl chitosan (HBC) hydrogels to produce aEB/HBC composite hydrogels. The aEB/HBC composite hydrogels exhibited reversible temperature-sensitive phase transition behavior and a hybrid porous network.

Enhancing photocatalytic CO reduction with TiO-based materials: Strategies, mechanisms, challenges, and perspectives.

The concentration of atmospheric CO has exceeded 400 ppm, surpassing its natural variability and raising concerns about uncontrollable shifts in the carbon cycle, leading to significant climate and environmental impacts. A promising method to balance carbon levels and mitigate atmospheric CO rise is through photocatalytic CO reduction. Titanium dioxide (TiO), renowned for its affordability, stability, availability, and eco-friendliness, stands out as an exemplary catalyst in photocatalytic CO reduction.

Longitudinal study on blood and biochemical indexes of Tibetan and Han in high altitude area.

Objective: This study aims to review the blood routine and biochemical indicators of the plateau population for three consecutive years, and analyze the impact of the plateau on these blood indicators of the Tibetan population and the Han immigrant population.

Method: These parameters were extracted from the Laboratory Department of Ali District People's Hospital in Tibet from January 2019 to December 2021, including blood routine, liver and kidney function, blood lipids, myocardial enzyme spectrum, and rheumatic factor indicators. Changes in these parameters were analyzed over 3 consecutive years according to inclusion and exclusion criteria.

Pyripyropene U, a new alkaloid from the sponge-derived fungus sp. SCSIO41420.

One new alkaloid, named pyripyropene U (), and six known natural products (-) were obtained from the marine sponge-derived fungus sp. SCSIO41420. Their structures were determined by detailed nuclear magnetic resonance (NMR) and mass spectroscopic (MS) analyses, while the absolute configurations of the new compound were unambiguously confirmed by theoretical electronic circular dichroism (ECD) calculation.

Recent Advances of Constructing Metal/Semiconductor Catalysts Designing for Photocatalytic CO Hydrogenation.

With the development of the world economy and the rapid advancement of global industrialization, the demand for energy continues to grow. The significant consumption of fossil fuels, such as oil, coal, and natural gas, has led to excessive carbon dioxide emissions, causing global ecological problems. CO hydrogenation technology can convert CO into high-value chemicals and is considered one of the potential ways to solve the problem of CO emissions.

Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX.

Unlabelled: Although external beam radiotherapy (xRT) is commonly used to treat central nervous system (CNS) tumors in patients of all ages, young children treated with xRT frequently experience life-altering and dose-limiting neurocognitive impairment (NI) while adults do not. The lack of understanding of mechanisms responsible for these differences has impeded the development of neuroprotective treatments. Using a newly developed mouse model of xRT-induced NI, we found that neurocognitive function is impaired by ionizing radiation in a dose- and age-dependent manner, with the youngest animals being most affected.

Applications of BiOX in the Photocatalytic Reactions.

BiOX (X = Cl, Br, I) families are a kind of new type of photocatalysts, which have attracted the attention of more and more researchers. The suitable band gaps and their convenient tunability via the change of X elements enable BiOX to adapt to many photocatalytic reactions. In addition, because of their characteristics of the unique layered structure and indirect bandgap semiconductor, BiOX exhibits excellent separation efficiency of photogenerated electrons and holes.

Light Control-Induced Oxygen Vacancy Generation and In Situ Surface Heterojunction Reconstruction for Boosting CO Reduction.

The weak adsorption of CO and the fast recombination of photogenerated charges harshly restrain the photocatalytic CO reduction efficiency. The simultaneous catalyst design with strong CO capture ability and fast charge separation efficiency is challenging. Herein, taking advantage of the metastable characteristic of oxygen vacancy, amorphous defect BiOCO (named BOC) was built on the surface of defect-rich BiOBr (named BOB) through an in situ surface reconstruction progress, in which the CO in solution reacted with the generated Bi around the oxygen vacancies.

Milnesium guanyinensis sp. nov. (Eutardigrada: Apochela) from Yunnan, China.

A new species from China, Milnesium guanyinensis sp. nov. (Tardigrada: Eutardigrada: Apochela: Milnesiidae), is described by means of classical taxonomic analysis, i.

, a New Tardigrade Species in the Complex from China.

In this paper we describe , a new tardigrade species of the complex from southern China. We used the traditional morphology-based taxonomic analysis, supported by detailed morphometrics, light microscopy imaging, scanning electron microscopy, and analysis of four genetic markers (18S rRNA, 28S rRNA, and ITS-2). sp.

Supercharged CO Photothermal Catalytic Methanation: High Conversion, Rate, and Selectivity.

To overcome the thermodynamic and kinetic impediments of the Sabatier CO methanation reaction, the process must be operated under very high temperature and pressure conditions, to obtain an industrially viable conversion, rate, and selectivity. Herein, we report that these technologically relevant performance metrics have been achieved under much milder conditions using solar rather than thermal energy, where the methanation reaction is enabled by a novel nickel-boron nitride catalyst. In this regard, an in situ generated HOB⋅⋅⋅B surface frustrated Lewis's pair is considered responsible for the high Sabatier conversion 87.

Skeletal myotube-derived extracellular vesicles enhance itaconate production and attenuate inflammatory responses of macrophages.

Introduction: Macrophages play an important role in the innate immunity. While macrophage inflammation is necessary for biological defense, it must be appropriately controlled. Extracellular vesicles (EVs) are small vesicles released from all types of cells and play a central role in intercellular communication.

Prognostic value of serum α-HBDH levels in patients with lung cancer.

Background: The purpose of our study is to investigate the expression level and prognostic value of serum α-hydroxybutyrate dehydrogenase (α-HBDH) in lung cancer (LC) patients.

Method: LC patients treated in the Department of Oncology, Shaanxi Provincial Cancer Hospital from January 2014 to December 2016 were included in this study, all of whom underwent serological detection of α-HBDH prior to admission, and were enrolled in follow-up 5-year survival. Comparing the differences between high group and normal groups based on α-HBDH and LDH expression via clinicopathological parameters and laboratory data.

p53-mediated metabolic response to low doses of ionizing radiation.

Purpose: Unlike treatment with high doses of radiation that causes considerable DNA damage resulting in injury and p53 activation, exposure of cells or whole animals to low doses of radiation (LDR, ∼10cGy) can induce a protective radio adaptive response. Despite ample information about the contribution of the p53 pathway to high doses of radiation-induced effects, our understanding of the role of p53 in LDR-induced response remains incomplete. This review provides a brief summary of the p53 response to LDR exposure focusing on metabolic regulation.

Analysis of the prognostic, diagnostic and immunological role of HSP90α in malignant tumors.

Heat shock protein 90α (HSP90α) encoded by the HSP90AA1 gene, is the stress inducible isoform of the molecular chaperone HSP90, and was demonstrated as a promising hallmark to diagnose, prognosis in malignant tumors. This study is to evaluate the value of HSP90α in diagnosis, prognosis and immunotherapy of malignant tumors by investigating the expression of HSP90α in plasma of various tumors and analyzing the expression of HSP90α at gene and protein levels pan-cancer database. We founded that levels of HSP90α in malignant tumors groups were significantly higher than healthy controls in serum.

Remnant Cholesterol and the Risk of Coronary Artery Calcium Progression: Insights From the CARDIA and MESA Study.

Background: Remnant cholesterol (RC) contributes to residual risk of atherosclerotic cardiovascular disease, but population-based evidence on the prospective relationship between RC and coronary artery calcium (CAC) progression is rare.

Methods: We pooled data obtained from 6544 atherosclerotic cardiovascular disease-free individuals from the CARDIA study (Coronary Artery Risk Development in Young Adults; n=2635) and MESA (Multi-Ethnic Study of Atherosclerosis; n=3909), with a mean±SD age of 47.2±19.

Diagnostic value of HSP90α and related markers in lung cancer.

Purpose: To investigate the expression of heat shock protein 90α (HSP90α) in patients with lung cancer (LC) and the clinical value of HSP90α and other related markers in the diagnosis of LC.

Methods: Of 335 patients enrolled in the study cohort, 175 were screened for LC and 160 were healthy (HC). The plasma levels of HSP90α and related markers (CEA, NSE, CYFRA21-1 and ProGRP) were detected in all individuals in the cohort by enzyme-linked immunosorbent assay (ELISA).

The Basally Expressed p53-Mediated Homeostatic Function.

Apart from mutations in the gene, p53 functions can be alternatively compromised by a decrease in nuclear p53 protein levels or activities. In accordance, enhanced p53 protein turnover due to elevated expression of the critical p53 E3 ligase MDM2 or MDM2/MDMX is found in many human cancers. Likewise, the HPV viral E6 protein-mediated p53 degradation critically contributes to the tumorigenesis of cervical cancer.