Publications by authors named "ZhiMin Xu"

Calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic epithelial tumor characterized by the presence of amyloid material within the tumor that can undergo calcification. CEOT affects individuals across a broad age range, typically between 20 and 60 years, with an average onset age of 40 years. However, it is extremely rare in children and adolescents.

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Background: Although the information on the validation status of electronic sphygmomanometer (ES) devices in use in health care institutions and households is much more clinically relevant than that of ES models available on the market, it remains insufficient.

Methods: A national survey was conducted across all administrative regions of mainland China to assess the validation status of ESs. Fifty-eight cities were selected with stratification by municipality, provincial capital, and other cities, and health care institutions and households in each city were chosen by convenience to identify ES devices in use according to the study protocol.

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The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.

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Introduction: Effective health management is crucial for elderly patients with coronary heart disease (CHD). This study applied a Psycho-Cardiology model to CHD management, aiming to assess psychological stress among patients with mild CHD and identify potential influencing factors to provide substantiating evidence.

Methods: This longitudinal study was based on a 9-year follow-up program of a community population in Shanghai, China.

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  • Obesity and type 2 diabetes pose major public health issues that affect global health significantly.
  • The focus of effective treatments is shifting toward the central nervous system and how it regulates metabolism, especially using incretin-based medications.
  • This review aims to summarize the latest research on the neural pathways related to key receptors involved in metabolic control, specifically glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide, and glucagon.
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  • Microplastics contamination in agricultural soils affects carbon and nitrogen cycles, leading to altered greenhouse gas emissions.
  • The presence of microplastics decreases soil water retention, which results in increased CO, CH₄, and NO emissions, while also enhancing soil structure and organic carbon storage.
  • Changes in microbial communities due to microplastics impact enzyme activity related to carbon and nitrogen processes, further complicating greenhouse gas dynamics and highlighting the need for better environmental management.
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  • Type I IFNs play a crucial role in the effectiveness of radiotherapy (RT), but tumor cells have developed mechanisms to inhibit their production, which is not fully understood.
  • A study using CRISPR screening identified hemeoxygenase 1 (HO-1) as a key regulator that disrupts the STING pathway and impairs the production of IFN-I during RT.
  • Targeting HO-1 could improve the efficacy of RT by enhancing immune response, as high levels of HO-1 were linked to worse patient outcomes post-RT in various tumors.
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We present a versatile nickel-electrocatalytic deaminative cross-coupling platform for the efficient construction of C(sp)-C(sp) and C(sp)-C(sp) bonds from readily available alkyl bistriflimides. This methodology involves the assembly of two leaving groups on alkyl amines to form alkyl bistriflimides, followed by their effective coupling with a wide range of alkyl halides, alkyl pseudohalides, aryl halides, and alkenyl halides under electrochemical reductive conditions. Moreover, the successful application of electrochemical reductive relay cross-coupling and transition metal-free cross-electrophile coupling further demonstrates the versatility of alkyl bistriflimides as valuable building blocks in organic synthesis.

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  • - This study created a biochar-loaded material with nitrogen-fixing bacteria (BAc) to reduce cadmium (Cd) levels in soil and promote plant growth, specifically in lettuce.
  • - BAc enhanced Cd adsorption by forming stable complexes and activating beneficial biochar groups, leading to significant increases in nitrogen uptake (up to 72.47%) and biomass (up to 107.32%).
  • - Additionally, BAc improved the microbial community in the soil, increasing diversity and promoting organisms that assist with nitrogen fixation and Cd immobilization, while also lowering Cd bioavailability by up to 46.42%.
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γ-Glutamyl transpeptidase (GGT) in shoot (TS) was extracted and purified through salt precipitation, ion-exchange column, and gel filtration chromatography methods. The GGT had two peptides with M.W.

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  • * Researchers analyzed data from 565 diabetic patients and found significantly higher levels of carbohydrate antigen 199 (CA199) in DKA and carcinoembryonic antigen (CEA) in HHS, alongside other clinical laboratory findings indicating altered metabolic and organ function.
  • * The results suggest that elevated CA199 in DKA is linked to acidosis, while elevated CEA in HHS may relate to iron balance, with osmolarity identified as a key
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Objective: We aim to examine and reestablish the correlational and linear regression relationships, as well as the predictive value, between the significant facial and tongue features and the metabolic parameters in type 2 diabetes mellitus (T2DM).

Materials And Methods: From March to May 2024, we studied 269 patients with T2DM in the endocrinology department of Shanghai Pudong Hospital. The patients' facial and tongue characteristics were sampling by a tongue imaging device equipped with artificial intelligence (AI) (XiMaLife, Sinology, China) of automated and advanced machine learning algorithms.

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Objectives: To investigate the variation in bone turnover biomarkers among patients with type 2 diabetes (T2D) and low triiodothyronine levels (Low T3 syndrome).

Materials And Methods: This retrospective analytic study included 418 inpatient records from Shanghai Pudong Hospital covering the years 2021 to 2023. Laboratory data related to metabolic and bone turnover biomarkers in patients were analyzed with T2D and the low T3 syndrome.

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Plant-growth-promoting rhizobacteria (PGPR) play an important role in plant growth and rhizosphere soil. In order to evaluate the effects of PGPR strains on tea plant growth and the rhizosphere soil microenvironment, 38 PGPR strains belonging to the phyla Proteobacteria with different growth-promoting properties were isolated from the rhizosphere soil of tea plants. Among them, two PGPR strains with the best growth-promoting properties were then selected for the root irrigation.

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Objective: Chronic inflammation and oxidative stress mediate the pathological progression of diabetic complications, like diabetic retinopathy (DR), peripheral neuropathy (DPN) and impaired wound healing. Studies have shown that treatment with a stable form of arginase 1 that reduces l-arginine levels and increases ornithine and urea limits retinal injury and improves visual function in DR. We tested the therapeutic efficacy of PEGylated arginine deiminase (ADI-PEG20) that depletes l-arginine and elevates l-citrulline on diabetic complications in the db/db mouse model of type 2 diabetes (T2D).

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Precise developmental timing control is essential for organism formation and function, but its mechanisms are unclear. In , the microRNA critically regulates developmental timing by post-transcriptionally downregulating the larval-stage-fate controller LIN-14. However, the mechanisms triggering the activation of expression toward the end of the first larval stage remain unknown.

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Conventional methods, such as freshwater dilution and ammonia stripping, have been widely employed for microalgae-based piggery wastewater (PW) treatment, but they cause high freshwater consumption and intensive ammonia loss, respectively. This present work developed a novel fast microbial nitrogen-assimilation technology by integrating nitrogen starvation, zeolite-based adsorption, pH control, and co-culture of microalgae-yeast for the PW treatment. Among them, the nitrogen starvation accelerated the nitrogen removal and shortened the treatment period, but it could not improve the tolerance level of microalgal cells to ammonia toxicity based on oxidative stress.

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Objective: Previous studies have indicated that there is an association between cervical cerclage and type of suture material. However, it is still unclear which suture material can provide the greatest benefit to patients who have undergone cerclage. This study investigated the effect of two different suture materials (Mersilene tape vs braided suture) used for transvaginal cervical cerclage placement on maternal outcomes of women with cervical insufficiency.

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Article Synopsis
  • This study investigates the information needs of cardiac patients using the Information Needs in Cardiac Rehabilitation short version (INCR-S) scale across different global regions.
  • It involved 1,601 patients from 19 countries and found that while knowledge of cardiac health topics was rated highly important, knowledge sufficiency varied significantly, especially between high- and middle-income countries.
  • The INCR-S scale proved to be a valid and reliable tool, revealing crucial gaps in patients’ knowledge regarding topics like medications, nutrition, and support resources.
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Whether stem-cell-like cancer cells avert ferroptosis to mediate therapy resistance remains unclear. In this study, using a soft fibrin gel culture system, we found that tumor-repopulating cells (TRCs) with stem-cell-like cancer cell characteristics resist chemotherapy and radiotherapy by decreasing ferroptosis sensitivity. Mechanistically, through quantitative mass spectrometry and lipidomic analysis, we determined that mitochondria metabolic kinase PCK2 phosphorylates and activates ACSL4 to drive ferroptosis-associated phospholipid remodeling.

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In the severe pollution area of nanoplastics (NPs) and cadmium ions (Cd), the joint effects of their high environmental concentrations on primary producers may differ from those of low environmental doses. Thus, we investigated the physiological changes, cell morphology, molecular dynamic simulation, phenotypic interactions, and metabolomics responses of C. pyrenoidosa to high environmental concentrations of NPs and Cd after 12-d acclimation.

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Ultraviolet light (UV)-assisted advanced oxidation processes (AOPs) are commonly used to degrade organic contaminants. However, this reaction system's extensive comprehension of the degradation mechanisms and toxicity assessment remains inadequate. This study focuses on investigating the degradation mechanisms and pathways of bisphenol A (BPA), generation of reactive oxygen species (ROS), and toxicity of degradation intermediates in UV/PDS/ferrous composites (FeO) systems.

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Microplastics (MPs) and heavy metals often coexist in soil, drawing significant attention to their interactions and the potential risks of biological accumulation in the soil-plant system. This paper comprehensively reviews the factors and biochemical mechanisms that influence the uptake of heavy metals by plants, in the existence of MPs, spanning from rhizospheric soil to the processes of root absorption and transport. The paper begins by introducing the origins and current situation of soil contamination with both heavy metals and MPs.

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