Synopsis of recent research by authors named "ZhiJun Dai"
- ZhiJun Dai's recent research prominently focuses on novel therapeutic strategies in cancer treatment, particularly emphasizing the role of immune modulation and cytokine signaling in enhancing anti-tumor responses, as demonstrated in studies evaluating anti-TGF-β/PD-L1 bispecific antibodies and the impact of IL-10 on mammary carcinoma.
- His work also investigates the mechanisms of neurodegenerative diseases like Parkinson's, utilizing engineered nanosheets to inhibit ferroptosis through targeting the labile iron pool and addressing α-synuclein aggregation, highlighting the potential for innovative materials in therapeutic applications.
- Additionally, Dai has contributed to understanding the prognostic implications of cuproptosis in breast cancer, comparing neoadjuvant endocrine treatment outcomes, and elucidating the role of specific kinases in aggressive breast cancer subtypes, all aimed at discovering effective biomarkers and treatment modalities.