Rational Design and Application of Breath Sensors for Healthcare Monitoring.

Biomarkers contained in human exhaled breath are closely related to certain diseases. As a noninvasive, portable, and efficient health diagnosis method, the breath sensor has received considerable attention in recent years for early disease screening and prevention due to its user-friendly and easy-accessible features. Although some key challenges have been addressed, its capability to precisely monitor specific biomarkers of interest and its physiological relevance to health metrics is still to be ascertained.

Chinese consensus report on the assessment and management of obstructive sleep apnea in patients with cardiovascular disease: 2024 edition.

As cardiovascular disease (CVD) incidence and mortality rates continue to rise in China, the importance of identifying and managing CVD risk factors grows. Obstructive sleep apnea (OSA) is a prevalent sleep-related breathing disorder, affecting an estimated 936 million individuals aged 30-69 worldwide, with China leading globally with about 176 million affected. Increasing research indicates a close association between OSA and the onset and progression of various CVD, significantly affecting outcomes.

Effects of Straw Addition on Soil Priming Effects Under Different Tillage and Straw Return Modes.

This study aims to investigate the impact of straw addition on soil activation effects under different tillage practices, providing a scientific basis for establishing reasonable straw return measures in the southern Northeast Plain, thus enhancing soil fertility, and mitigating greenhouse effects. Soil samples were collected from various straw return practices that were conducted continuously for two years as follows: rotary tillage without straw return (RTO), deep tillage combined with straw incorporation (PT), rotary tillage with straw incorporation (RT), and no-till with straw cover (NT). The samples were incubated in the dark at 25 °C for 70 days.

Effects of Genetic Polymorphism in the Gene on Milk Fat Traits and Relevance to Lipid Metabolism in Bovine Mammary Epithelial Cells.

Milk fat is an important indicator for evaluating milk quality and a symbol of the core competitiveness of the dairy industry. It can be improved through genetic and feed management factors. Interferon alpha-inducible protein 27 () was found to be differentially expressed when comparing the transcriptome in high- and low-fat bovine mammary epithelial cells (bMECs) in our previous research.

[Retracted] PLGA/poloxamer nanoparticles loaded with EPAS1 siRNA for the treatment of pancreatic cancer and .

Following the publication of this article, a concerned reader drew to the Editor's attention that, in the tumor tissue images shown in Fig. 5A and B on p. 1001, there were two pairs of overlapping data panels, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the same original sources.

Design and application of inclined tensioned steel cantilevered scaffolding.

In order to reduce the cost of scaffolding usage in engineering projects as much as possible under the premise of safety and rationality, while avoiding the risk of leakage caused by holes left in the building structure by the scaffolding, a type of inclined tensioned steel cantilevered scaffolding is proposed based on the stress characteristics of traditional cantilevered scaffolding. Considering the actual construction characteristics, a comprehensive approach involving theoretical analysis, on-site field tests, and finite element methods is adopted to clarify the full-process design method of the inclined tensioned steel cantilevered scaffolding. Additionally, recommendations are provided for the practical engineering design and application of the inclined tensioned steel cantilevered scaffolding.

The association between physical activity and positive affect in adolescents: the chain mediating role of psychological resilience and regulatory emotional self-efficacy.

Previous studies have indicated the positive impact of physical activity on positive affect in adolescents. However, the psychological mechanism is still under-explored. The current study aims to investigate the mediating role of psychological resilience and regulatory emotional self-efficacy on the relationship between physical activity and positive affect.

Ternary Moral Empathy Model from the Perspective of Intersubjective Phenomenology.

The phenomenon of empathy is an intersubjective process of feeling and a particular form of intentionality. Moral empathy refers to a type of empathy that can trigger moral action, with the embodied intersubjectivity laying the foundation for its emergence. This paper attempts to propose a comprehensive theoretical model of moral empathy from the perspective of intersubjective phenomenology, which includes the following.

Phlorotannin Alleviates Liver Injury by Regulating Redox Balance, Apoptosis, and Ferroptosis of Broilers under Heat Stress.

Heat stress (HS) poses a great challenge to the poultry industry by inducing oxidative damage to the liver, endangering the health and production of broilers. As an important type of seaweed polyphenols, phlorotannin has been shown to have antioxidant properties. The present study evaluated the protective effects of dietary phlorotannin on HS-induced liver injury in broilers based on oxidative damage parameters.

Prenatal diagnosis of monozygotic twins with phenotypic differences in chromosome 17q12 deletion syndrome.

We present a case study highlighting prenatal ultrasound findings in monozygotic twins with chromosome 17q12 deletion syndrome. Fetus A exhibited bilateral fetal pyelectasis and talipes equinovarus, while fetus B showed hyperechogenic kidneys. Despite sharing the same de novo variant, the twins displayed distinct clinical phenotypes, suggesting the presence of non-genetic factors influencing the phenotypic variability of this syndrome.

Osteoporosis treatment: current drugs and future developments.

Osteoporosis is a common systemic metabolic disease characterized by a decrease in bone density and bone mass, destruction of bone tissue microstructure, and increased bone fragility leading to fracture susceptibility. Pharmacological treatment of osteoporosis is the focus of current research, and anti-osteoporosis drugs usually play a role in inhibiting bone resorption, promoting bone formation, and having a dual role. However, most of the drugs have the disadvantages of single target and high toxic and side effects.

Five commonly used traditional Chinese medicine formulas in the treatment of ulcerative colitis: A network meta-analysis.

Background: Currently, traditional Chinese medicine (TCM) formulas are commonly being used as adjunctive therapy for ulcerative colitis in China. Network meta-analysis, a quantitative and comprehensive analytical method, can systematically compare the effects of different adjunctive treatment options for ulcerative colitis, providing scientific evidence for clinical decision-making.

Aim: To evaluate the clinical efficacy and safety of commonly used TCM for the treatment of ulcerative colitis (UC) in clinical practice through a network meta-analysis.

Molecularly imprinted polymer-based electrochemical sensor for rapid detection of masked deoxynivalenol with Mn-doped CeO nanozyme as signal amplifier.

Deoxynivalenol-3-glucoside (D3G), the masked form of the important mycotoxin deoxynivalenol (DON), displays potential toxicity but is difficult to control owing to the lack of rapid detection methods. Herein, an innovative molecularly imprinted polymer (MIP)-based electrochemical sensor was developed for the rapid detection of D3G. MIP, an efficient recognition element for D3G, was electropolymerized using o-phenylenediamine based on a surface functional monomer-directing strategy for the first time.

A multifunctional gingival retraction cord with antibacterial and hemostasis properties based on Chitosan/Propolis/Tranexamic acid for dental treatment.

A novel gingival retraction cord named P/TA@CSy was prepared using chitosan yarns (CSy) loaded with tranexamic acid (TA) and Propolis (P). P/TA@CSy has good toughness with a breaking strength of 41.3 Pa, benefiting from the twisting structure and Propolis coating.

Effects of malnutrition on disease severity and adverse outcomes in idiopathic pulmonary arterial hypertension: a retrospective cohort study.

Background: Malnutrition is common in patients with chronic cardiovascular disease and is associated with significantly higher all-cause mortality. Approximately one-third of patients with heart failure are malnourished. However, the relationship between malnutrition and idiopathic pulmonary arterial hypertension (IPAH) remains unclear.

Lipid Regulatory Element Interact with on Mitochondrial Bioenergetics in Bovine Adipocyte Differentiation and Lipometabolism.

The gene is a critical factor in animal physiological processes and has been shown to affect insulin resistance and fat accumulation in mammals. Nevertheless, little research has been conducted on its precise functions in lipid metabolism and adipogenic differentiation in beef cattle. This study analyzed the expression of and miR-199a-3p during bovine preadipocyte differentiation.

Spatiotemporal Regulation of Cell Fate in Living Systems Using Photoactivatable Artificial DNA Membraneless Organelles.

Coacervates formed by liquid-liquid phase separation emerge as important biomimetic models for studying the dynamic behaviors of membraneless organelles and synchronously motivating the creation of smart architectures with the regulation of cell fate. Despite continuous progress, it remains challenging to balance the trade-offs among structural stability, versatility, and molecular communication for regulation of cell fate and systemic investigation in a complex physiological system. Herein, we present a self-stabilizing and fastener-bound gain-of-function methodology to create a new type of synthetic DNA membraneless organelle (MO) with high stability and controlled bioactivity on the basis of DNA coacervates.

Intelligent Gas Detection: g-CN/Polypyrrole Decorated Alginate Paper as Smart Selective NH/NO Sensors at Room Temperature.

Chemiresistive NH/NO sensors are attracting considerable attention for use in air-conditioning systems. However, the existing sensors suffer from cross-sensitivity, detection limit, and power consumption, owing to the inadequate charge-transfer ability of gas-sensing materials. Herein, we develop a flexible NH/NO sensor based on graphitic carbon nitride/polypyrrole decorated alginate paper (AP@g-CN/PPy).

Predicting Kawasaki disease shock syndrome in children.

Background: Kawasaki disease shock syndrome (KDSS) is a critical manifestation of Kawasaki disease (KD). In recent years, a logistic regression prediction model has been widely used to predict the occurrence probability of various diseases. This study aimed to investigate the clinical characteristics of children with KD and develop and validate an individualized logistic regression model for predicting KDSS among children with KD.