Publications by authors named "ZhiCheng Chen"

Agriculture is a major contributor to global greenhouse gas emissions, highlighting the urgent need for effective carbon reduction strategies. This study presents an innovative integrated model that employs Fermatean Neutrosophic Set in conjunction with the Weighted Influence Nonlinear Gauge System and the Analytic Hierarchy Process combined with the Entropy Weight Method to assess key factors influencing agricultural carbon reduction. Our study delineates the hierarchical importance of factors influencing carbon emissions, with carbon emission reduction policy (τ4) emerging as the paramount factor, attributed a value of 0.

View Article and Find Full Text PDF

Leukopenia, marked by diminished white blood cell (WBC) counts, presents significant challenges in the management of hematological malignancies and immunocompromised patients. This study evaluated the therapeutic potential of miltefosine (MFS), a phospholipid analogue, for treating leukopenia. In vitro studies using HL60 and NB4 cells revealed that MFS effectively promoted neutrophil differentiation and function, evidenced by the upregulation of surface markers CD11b, CD11c, CD14, and CD15, as well as enhanced bactericidal activity assessed through the NBT reduction assay.

View Article and Find Full Text PDF

, C. Wang & Chang Y. Yang, a desert-adapted shrub, is recognized for its exceptional drought tolerance and plays a vital role in ecosystem maintenance.

View Article and Find Full Text PDF

The significance of ultrafast laser-induced energy and mass transfer at interfaces has been growing in the field of nanoscience and technology. Nevertheless, the complexity arising from non-linear and non-equilibrium optical-thermal-mechanical interactions results in intricate transitional behaviors. This complexity presents challenges when attempting to analyze these phenomena exclusively through modeling or experimentation.

View Article and Find Full Text PDF
Article Synopsis
  • * A study analyzed the outcomes of 103 patients (aged 21 days to 63 years) who underwent transcatheter intervention for CoA over a 12-year span, focusing on clinical and echocardiographic data.
  • * Results showed significant improvements, including lower systolic blood pressure and reduced left ventricular mass, with a high survival rate of 98.1% and minimal need for reintervention, supporting the efficacy of the treatment and innovative techniques used.
View Article and Find Full Text PDF

This paper identifies nine factors affecting agricultural sustainable development by reading extensive literature and invites five experts to assess these factors using the pythagorean neutrosophic linguistic variable. Some of these factors can directly reduce the environmental footprint of agriculture, improve soil health, and promote biodiversity, while others can indirectly integrate to support the adoption of sustainable practices, further mitigating environmental degradation. Collectively, these factors reinforce ecological balance and play a critical role in advancing agricultural sustainable development.

View Article and Find Full Text PDF

The recent advancements on membrane protein degraders (MPDs) have broadened the applicability of proteolysis-targeting chimeras (PROTACs) beyond intracellular proteins to include the previously "undruggable" cell-surface targets. However, the potential toxicity of MPDs caused by undesired off-target degradation poses a significant challenge to clinical deployment, mirroring concerns associated with PROTACs. Here, we introduce a conditionally activatable membrane protein degrader (Pro-MPD), which leverages the specificity and high affinity of biparatopic nanobodies combined with a tumor microenvironment-activated cell-penetrating peptide (Pro-CPP) to achieve on-target activated internalization and degradation of PD-L1 within tumor sites.

View Article and Find Full Text PDF

Silicon photonic devices are key components in optical imaging and sensing for communication, and the development of silicon-based photodetectors with ideal performance in the visible and infrared spectral ranges can promote the application of silicon photonics in various photoelectronic systems. Here, a Au-doped black silicon photodetector was prepared by a femtosecond laser direct writing technique. The conical micro-/nanostructures with different sizes were produced by different laser fluence irradiation.

View Article and Find Full Text PDF

Background: Vascular invasion (VI) is closely related to the metastasis, recurrence, prognosis, and treatment of gastric cancer. Currently, predicting VI preoperatively using traditional clinical examinations alone remains challenging. This study aims to explore the value of radiomics analysis based on preoperative enhanced CT images in predicting VI in gastric cancer.

View Article and Find Full Text PDF

Background: Syphilis is an infectious disease caused by that can invade the central nervous system, causing encephalitis. Few cases of anti-N-methyl-D-aspartate receptor autoimmune encephalitis (AE) secondary to neurosyphilis have been reported. We report a neurosyphilis patient with anti-γ-aminobutyric acid-B receptor (GABAR) AE.

View Article and Find Full Text PDF

Arsenic is a worldwide environmental pollutant that can impair human health. Previous studies have identified mental disorders induced by arsenic, but the environmental exposure concentrations in the early life stages associated with these disorders are poorly understood. In the present study, early-life stage zebrafish were used to explore the effects on mental disorders under 'environmental standard limit concentrations' arsenic exposures of 5, 10, 50, 150, and 500 μg/L.

View Article and Find Full Text PDF

Background: The calibrator in immunoassay plays an essential role in diagnosing Alzheimer's disease (AD). Presently, the most well-studied biomarkers for AD diagnosis are three phosphorylated Tau (p-Tau): p-Tau231, p-Tau217, and p-Tau181. Glycogen synthase-3beta (GSK3β)-phosphorated Tau-441 is the most commonly used calibrator for p-Tau immunoassays.

View Article and Find Full Text PDF

In femtosecond laser fabrication, the laser-pulse train shows great promise in improving processing efficiency, quality, and precision. This research investigates the influence of pulse number, pulse interval, and pulse energy ratio on the lateral and longitudinal ultrafast melting process using an experiment and the molecular dynamics coupling two-temperature model (MD-TTM model), which incorporates temperature-dependent thermophysical parameters. The comparison of experimental and simulation results under single and double pulses proves the reliability of the MD-TTM model and indicates that as the pulse number increases, the melting threshold at the edge region of the laser spot decreases, resulting in a larger diameter of the melting region in the 2D lateral melting results.

View Article and Find Full Text PDF

Solar-driven viscosity reduction of highly viscous crude oil has emerged as an environmentally friendly method to address large-scale oil spills. However, the challenge lies in the limited availability of sunlight during cloudy days and at night, which hinders the effectiveness of green advanced porous materials. This study developed all-weather-available advanced porous materials in the form of loofah-like structured porous frame composed of 1H, 1H, 2H, 2H-perfluorooctyltriethoxysilane/MXene/carbon nanotubes (CNTs)/sodium alginate (SA)/carboxymethyl cellulose sodium (NaCMC).

View Article and Find Full Text PDF
Article Synopsis
  • Soybean is a vital global oilseed crop due to its high unsaturated fatty acid content, which directly affects its economic value.
  • Genetic variation in soybean cultivars leads to significant differences in seed oil content, but the specific genes regulating this trait are not fully understood.
  • This study identified the GmFATA1B gene as a key regulator of seed oil content and composition, and manipulating this gene can potentially improve soybean oil characteristics.
View Article and Find Full Text PDF

Aerogel, known as one of the remarkable materials in the 21st century, possesses exceptional characteristics such as high specific surface area, porosity, and elasticity, making it suitable for a diverse range of applications. In recent years, MXene-based aerogels and MXene composite aerogels as functional materials have solved some limitations of traditional aerogels, such as improving the electrical conductivity of biomass and silicon aerogels, further improving the energy storage capacity of carbon aerogels, enhancing polymer-based aerogels, etc. Consequently, extensive research efforts have been dedicated to investigating MXene-based aerogels, positioning them at the forefront of material science studies.

View Article and Find Full Text PDF

As industrial waste from aluminum production, red mud (RM) poses a severe threat to the local environment that needs to be appropriately utilized. The activation of iron oxide, which is abundant in RM, improves its effectiveness as a catalytic material for the degradation of organic pollutants. This study developed a novel activation approach by adding dithionite citrate bicarbonate (DCB) for Bisphenol A (BPA) degradation under aeration conditions.

View Article and Find Full Text PDF

Funiu Mountains are located in a transition region between warm temperate zone and northern subtropical region, where a variety of plant species are distributed with sensitive response to climate change. Their response characteristics to climate change are still unclear. We developed the basal area increment (BAI) index chronologies of , , and in the Funiu Mountains to examine their growth trend and their sensitivity to climatic change.

View Article and Find Full Text PDF

Unlabelled: Adaptations of ciliates to hypoxic environments have arisen independently several times. Studies on mitochondrion-related organelle (MRO) metabolisms from distinct anaerobic ciliate groups provide evidence for understanding the transitions from mitochondria to MROs within eukaryotes. To deepen our knowledge about the evolutionary patterns of ciliate anaerobiosis, mass-culture and single-cell transcriptomes of two anaerobic species, (class Armophorea) and cf.

View Article and Find Full Text PDF

A full understanding of the inactivated COVID-19 vaccine-mediated antibody responses to SARS-CoV-2 circulating variants will inform vaccine effectiveness and vaccination development strategies. Here, we offer insights into the inactivated vaccine-induced antibody responses after prime-boost vaccination at both the polyclonal and monoclonal levels. We characterized the VDJ sequence of 118 monoclonal antibodies (mAbs) and found that 20 neutralizing mAbs showed varied potency and breadth against a range of variants including XBB.

View Article and Find Full Text PDF
Article Synopsis
  • N-trifluoromethylsuccinimide (NTFS) is a newly developed reagent for trifluoromethylation, created using a silver-coupled method.
  • It has been successfully used to directly introduce trifluoromethyl groups to free aniline, resulting in a variety of products with good yields.
  • The approach was demonstrated through a gram-scale experiment and the synthesis of the drug Mabuterol, with a proposed radical mechanism supported by experimental evidence.
View Article and Find Full Text PDF

A protocol for metal and oxidant free photoredox catalyzed trifluoromethylation of 2-indazoles was developed by using Eosin Y as the photocatalyst and recoverable ionic liquids as the solvents. A series of trifluoromethylated products were obtained in moderate to good yields in this protocol under mild conditions. The reaction proceeded a free-radical mechanism with a broad substrate range, excellent regioselectivity, and good functional group tolerance.

View Article and Find Full Text PDF

This study was designed to evaluate the effects of different rice nutrient compounds on steamed bread's nutritional characteristics and sensory evaluation. The mixture design approach was used to research the interactions between different rice flours and wheat flours on the sensory evaluation of steamed bread. The arginine content of different rice flour (long-grained rice, polished round-grained rice, and black rice) was higher at 44.

View Article and Find Full Text PDF

Objective: Scavenger receptor A (SRA), a pattern recognition molecule, is implicated in immune response after acute brain injury. We strived to identify serum soluble SRA (sSRA) as a potential biomarker of prognosis after aneurysmal subarachnoid hemorrhage (aSAH).

Methods: In this prospective observational study, we quantified serum sSRA levels of 131 aSAH patients and 131 healthy controls.

View Article and Find Full Text PDF

Canopy conductance (g) is an important biophysical parameter closely related to ecosystem energy partitioning and carbon sequestration, which can be used to judge drought effect on forest ecosystems. It is very important to explore how soil moisture change affects the environmental control mechanism of g, especially in natural oak forests in Central China where frequent extreme precipitation (P) and drought will occur in a context of climate change. In this study, variations of g and its environmental control mechanisms in a warm-temperate forest over three consecutive years under different hydroclimatic conditions were examined by using eddy-covariance technique.

View Article and Find Full Text PDF