[Histomorphology of angiogenesis patterns in different areas of human astrocytomas].

Objective: To study angiogenesis patterns in the edematous area and the center of human astrocytomas by histological observation, and to reveal histological basis of vasculogenic mimicry.

Method: Tissue samples were drawn from the tumor center and the edematous area in 51 patients with human astrocytomas during operation MR and were examined by CD34 endothelial marker periodic acid-Schiff (PAS) dual staining.

Results: Vessels or capillaries stained by both PAS and CD34 were found in edematous areas of human astrocytomas.