Development and evaluation of a bivalent vaccine based on recombinant newcastle disease virus expressing infectious bursal disease virus VP2L-CH3-CH4 in SPF chickens.

Newcastle disease (ND) and infectious bursal disease (IBD) are two viral infectious diseases that are extremely damaging to the poultry industry and are widespread throughout the world. It is necessary to develop a safe and effective vaccine against IBD and ND because vaccination is an effective preventive measure. It has been discovered that recombinant proteins expressed by an expression system in which a fragment of mammalian Immunoglobulin G (IgG) Fragment crystallizable (Fc) is linked to a segment of a gene have antibody-like properties that increase the exogenous protein's serum half-life.

Inhibition of miR-22 enhanced the efficacy of icotinib plus pemetrexed in a rat model of non-small cell lung cancer.

Objectives: To investigate the role of miR-22 in the efficacy of combined icotinib (BPI-2009H) and pemetrexed (LY-231514) on tumor growth and apoptosis in rats with non-small cell lung cancer (NSCLC).

Materials And Methods: Rats were injected with HCC827 cells, which were transfected with anti-miR-22, followed by the treatment of BPI-2009H and/or LY-231514. MTT assay was used to detect the inhibition rate of HCC827 cells.

Results of surgical treatment for primary malignant melanoma of the esophagus: A multicenter retrospective study.

Objective: Few large-sample research data sets exist on long-term survival and prognostic factors among patients with primary malignant melanoma of the esophagus (PMME), a rare malignancy associated with poor outcomes. We sought to investigate postoperative survival and prognostic factors in patients with PMME.

Methods: We retrospectively analyzed long-term follow-up results for patients with PMME who underwent surgery at 10 Chinese centers between January 1998 and January 2018.

Clinical characteristics and survival of lung cancer patients associated with multiple primary malignancies.

Objectives: To investigate the characteristics and survival of lung cancer patients with additional malignant primary cancers.

Methods: Records of lung cancer patients newly diagnosed in Shanghai Pulmonary Hospital between January 2000 and January 2010 were retrospectively reviewed. Patients with second primary lung cancer and those with lung cancer only were included for detailed analysis.

Surgical treatment and prognosis of octogenarians with non-small cell lung cancer.

Objective: To explore the clinical characteristics, surgical treatment and prognosis of non-small cell lung cancer (NSCLC) among elderly patients over 80 years.

Methods: The clinical data, surgical methods, perioperative management, postoperative complications and prognosis of 52 NSCLC patients aged over 80 years were retrospectively analyzed.

Results: Out of 52 cases, 27 had a long-term smoking history (51.

[Surveillance of echinococcosis in high risk areas of Yixing City from 2008 to 2009].

An investigation was conducted retrospectively for echinococcosis (hydatid disease) in Yixing City from 2008 to 2009, the serum or fecal samples of suspected patients during the past 5 years and host animals were assessed by ELISA. There were 2 cases reported by network and 4 confirmed patients by investigation, and among the total 6 cases, 5 cases may be infected in the locality. The positive rates were 0.

[Combination of single-port thoracoscopy and laparoscopy for the treatment of esophageal carcinoma: report of 6 cases].

Objective: To study the feasibility and early results of radical resection of esophageal carcinoma using single-port thoracoscopy combined with laparoscopy.

Methods: From March 2010 to December 2010, 6 patients with esophageal carcinoma underwent radical resection by single-port thoracoscopy combined with laparoscopy in the General Hospital of People's Liberation Army. With the patients at a supine position, laparoscopy was performed to complete stomach mobilization and abdominal lymph node dissection.

Predictors of postoperative myasthenic crisis in patients with myasthenia gravis after thymectomy.

Background: Thymectomy is considered the most effective treatment in patients with myasthenia gravis. This study aimed to explore the predictors of postoperative myasthenic crisis in patients with myasthenia gravis after thymectomy.

Methods: Clinical records of 243 patients with myasthenia gravis who underwent thymectomy were reviewed retrospectively.

Diagnostic values of SCC, CEA, Cyfra21-1 and NSE for lung cancer in patients with suspicious pulmonary masses: a single center analysis.

We recruited 805 patients with suspicious pulmonary masses that were identified finally as lung cancer or benign pulmonary masses. The serum levels of four tumor markers, including squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), cytokeratin 19 fragment antigen 21-1 (Cyfra21-1) and neuron specific enolase (NSE) were tested for every patient. Though receiver operating characteristic (ROC) curves indicated unsatisfactory diagnostic power of those four tumor markers for lung cancer, 37.

Rhinoplasty in Chinese: management of lower dorsum and bulbous nasal tip.

Background: Bulbous nasal tips and lower dorsa are common facial features in Chinese people, and surgery to reshape these is frequently requested. The use of silicone implants in rhinoplasty has been widely used in China for many years, but is not suitable for patients seeking Caucasian tip shapes. The creation of an excessively high tip supported only by a silicone implant inevitably leads to implant extrusion.

[Treatment of scar contracture abnormality on the neck of the children with huge trapezius muscle flap expanded].

Objective: To seek a kind of safe and effective method to treat scar contracture abnormality on the neck of the children.

Methods: We take the trunk line of transverse cervical artery as the vessel pedicle, and shift huge trapezius muscle flap expanded to the neck in order to treat scar contracture abnormality on the neck of the children.

Results: Clinically, we applied this method to treat ten children who suffered from contracture abnormality on the neck, and not only provide enough skin soft tissue (the length may be beyond the midline) to treat the abnormality, but also make the flap alive, obtain the satisfying postoperative effect.

[Temporal three-point relief-tension suspension technique for facial rhytidectomy].

Objective: To evaluate a facial rhytidectomy technique to reduce the complications of temporal alopecia and incisional scar hyperplasia.

Methods: The 82 aged patients were divided into 2 groups in random way: group A in 46 with the use of the three-point relief-tension suspension technique and group B in 36 as control. In group A, the two point of every relief-tension suture was located respectively in the subcutis of the hairline and fascia under the incision.

[Latissimus dorsi transfer to restore thoracic malformation of Poland's syndrome].

Objective: To study the methods and points for attention of latissimus dorsi muscle flap transplantation to correct the thoracic malformation of Poland's syndrome.

Methods: From 1995 to 2003, 10 patients were diagnosed of Poland's syndrome with absence of pectoris major muscle in all patients. The latissimus dorsi muscle flap was exposed and transferred through a vertical lateral thoracic cut and a short cut beneath the axillary fold.

[Clinical characteristics and outcome of myasthenia gravis with and without thymoma after operation].

Objective: To explore the clinical characteristics and outcome of myasthenia gravis with and without thymoma after operation.

Methods: Two hundred and forty-three patients with myasthenia gravis surgically treated in our department from 1978 to 2003 were studied retrospectively. The clinical characteristics, complication, remission and survival were compared between myasthenia gravis with and without thymoma.