Matrine inhibits bladder cancer cell growth and invasion in vitro through PI3K/AKT signaling pathway: An experimental study.

Objective: To study the inhibitory effect of matrine on bladder cancer cell growth and invasion in vitro through PI3K/AKT signaling pathway.

Methods: Human T24 bladder cancer cell lines were cultured and treated with different doses of matrine (0.25 mg/mL, 0.

miR-21 targets and inhibits tumor suppressor gene PTEN to promote prostate cancer cell proliferation and invasion: An experimental study.

Objective: To study whether miR-21 targets and inhibits tumor suppressor gene PTEN can promote prostate cancer cell proliferation and invasion.

Methods: Prostate cancer cell lines PC-3 were cultured and divided into negative control group (NC group), miR-21 group, pcDNA3.1 group, miR-21+pcDNA3.

Percutaneous intrarenal marsupialization of symptomatic peripelvic renal cysts: a single-centre experience in China.

Unlabelled: OBJECTIVE.The aim of this study was to report the authors' experience with percutaneous intrarenal marsupialization of symptomatic peripelvic renal cysts.

Material And Methods: Thirty-one patients (16 male and 15 female, with a mean age of 49 years) with a peripelvic renal cyst associated with chronic flank or lumbar pain or urinary infection were selected for percutaneous intrarenal marsupialization with a 2 μm laser in the authors' centre from January 2005 to December 2010.

[Percutaneous nephroscopic 2 µm laser incision and drainage treatment of peripelvic renal cysts].

Objective: To explore the surgical approaches, efficacy and safety of percutaneous nephroscopic 2 µm laser incision and drainage in the treatment of peripelvic renal cysts.

Methods: The peripelvic renal cysts were punctured percutaneously. A 1.

[Extracorpreal shockwave lithotripsy in treatment of bilateral ureteral calculi with renal colic during emergency].

Objective: To evaluate the clinical efficacy of extracorporeal shockwave lithotripsy (ESWL) for bilateral ureteral stones with renal colic in emergency.

Methods: We retrospectively analyzed the clinical data of 86 patients suffered with sudden renal colic due to bilateral ureteral stones and treated with ESWL between January 2005 and January 2009.

Results: The success rate was 74.

[Three minimally invasive approaches for treatment of ureteral calculi: a comparative analysis of 326 cases].

Objective: To compare the therapeutic effect of 3 minimally invasive approaches for ureteral calculi removal and analyze their respective advantages and limitations.

Methods: A retrospective analysis was conducted in 326 patients receiving extracorporeal shock wave lithotripsy (ESWL), ureteroscopic lithotripsy (URL) or percutaneous nephrolithotripsy (PCNL) for ureteral calculi. The clinical data including the stone-free rate and complications were analyzed.

[Analysis of the outcome of extracorporeal shock wave lithotripsy for renal calculia].

Objective: To evaluate the factors affecting the efficacy of extracorporeal shock wave lithotripsy (ESWL) for renal calculi.

Methods: Between January, 2004 and January, 2007, 316 patients (212 men and 104 women) with renal stone underwent ESWL. The correlations of the patients' age, gender, body mass index (BMI), disease course, pain, hematuria, stone size, location, side, number and hydronephrosis to the outcome of the treatment was analyzed.

[Factors affecting the outcome of extracorporeal shockwave lithotripsy for upper urinary tract stones].

Objective: To investigate the factors affecting the efficacy of extracorporeal shockwave lithotripsy (ESWL) for upper urinary tract stones.

Methods: Between January 2003 and January 2006, 366 patients with upper urinary tract stone underwent ESWL, and the results were identified by regular KUB/IVU or ultrasonography and evaluated 3 months after the treatment. The treatment success was defined as complete clearance of the stones without residual fragments.

[Expressions of hypoxia inducible factor-1alpha and vascular endothelial growth factor in human renal cell carcinoma].

Objective: To explore the expression of hypoxia inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in renal cell carcinoma (RCC) and their relationship.

Methods: The expression of HIF-1alphaand VEGF was examined in 42 patients with renal cell carcinoma by SABC methods of immunohistochemistry.

Results: The positivity rate of HIF-1alpha was 57.

[Nephron-sparing surgery for small renal cell carcinoma: clinical analysis of 21 cases].

Objective: To evaluate the clinical effects of nephron-sparing surgery in patients with early-stage small renal cell carcinoma.

Methods: Nephron-sparing surgery was performed in 21 patients with renal cell carcinoma including 1 with solitary kidney, 3 with unilateral tumor and contralateral renal compromise, and 17 with unilateral tumor and normal contralateral kidney. The diameter of the tumors ranged from 1.