Numerical simulation on the effect of impeller radial gap on hemodynamics and hemocompatibility of a centrifugal blood pump.

Impeller radial gap is one of important parts within a blood pump, which may affect the hemodynamics and hemocompatibility. In this study, computational fluid dynamics method was performed to evaluate the impact of radial gap sizes. The volume of scalar shear stress decreased with radial gap sizes increasing.

A multi-constituent model for assessing the effect of impeller shroud on the thrombosis potential of a centrifugal blood pump.

Centrifugal blood pumps can be used for treating heart failure patients. However, pump thrombosis has remained one of the complications that trouble clinical treatment. This study analyzed the effect of impeller shroud on the thrombosis risk of the blood pump, and predicted areas prone to thrombosis.

Numerical investigation on the effect of impeller axial position on hemodynamics of an extracorporeal centrifugal blood pump.

Extracorporeal centrifugal blood pumps are used to treat cardiogenic shock. Owing to the imbalanced excitation or initial assembly configurations, the variation in the impeller axial position has the potential to affect the blood pump performance. This study compared the hydrodynamics and hemolysis outcomes at different impeller axial positions numerical simulations.

Experimental Investigation of Solar-Driven Hollow Fiber Membrane Liquid Dehumidification System.

The hollow fiber membrane modules act as dehumidifiers and regenerators to avoid gas-liquid entrainment problems in direct-contact dehumidification systems. A solar-driven hollow fiber membrane dehumidification experimental rig was designed to investigate its performance from July to September in Guilin, China. The dehumidification, regeneration, and cooling performance of the system between 8:30 and 17:30 are analyzed.

Dectin-1 rs3901533 and rs7309123 Polymorphisms Increase Susceptibility to Pulmonary Invasive Fungal Disease in Patients with Acute Myeloid Leukemia from a Chinese Han Population.

This study aimed to assess whether genetic variants of dendritic cell-associated C-type lectine-1 (Dectin-1), Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4), and myeloid differentiation primary response 88 (MyD88) influence the susceptibility to pulmonary invasive fungal disease (IFD) in patients with acute myeloid leukemia (AML) from a Chinese Han population. Eight single nucleotide polymorphisms (SNPs) of Dectin-1 (rs16910526, rs3901533, and rs7309123), TLR2 (rs5743708), TLR4 (rs4986790 and rs4986791) and MyD88 (rs4988453 and rs4988457) in the genomic DNA of 172 adult AML patients were genotyped. Pulmonary IFD was diagnosed as proven or probable according to the 2008 European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) consensus guidelines.

[Clinical Analysis of Driver Mutations in Patients with Ph Negative Myeloproliferative Neoplasms].

Objective: To explore the relationship between driver mutations and clinical characteristics in patients with Philadelphia chromosome (Ph) negative myeloproliferative neoplasms (MPN), so as to provide evidence for diagno-sis and treatment of the disease.

Methods: The clinical data of 410 patients with classic Ph negative MPN including 150 cases of polycythemia vera (PV), 188 cases of essential thrombocythemia (ET) and 72 cases of primary myelofibrosis (PMF) from January 2013 to December 2016 in Fujian Medical University Union Hospital were retrospectively analyzed. The PCR or DNA sequencing were used for JAK2 V617F, JAK2 exon12, CALR and MPL W515L/K mutation analyses, and follow-up information on patients was updated by direct phone call or follow-up in outpatient.

[Current Understanding of Myeloproliferative Neoplasm-Related Gene Mutations and Cytokine -Review].

Myeloproliferative neoplasm(MPN) is clonal hematopoietic stem cell disorder characterized by abnormal proliferation and expansion of one or more myeloid lineages. BCR-ABL-negative MPN includes polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF). The mutations of JAK2, CALR and MPL genes are involved in the pathogenesis of MPN that provided a more complete molecular diagnostic standard for MPN.

[Effects of excessive inorganic nitrogen on inorganic carbon system in seawater simulated experiments].

The influence of excessive inorganic nitrogen (NO3-, NH4+, NO2-) on the pH, inorganic carbon system and air-sea CO2 flux was studied in laboratory seawater simulation experiments. The result indicates that the excessive inorganic nitrogen significantly has an important influence on the inorganic carbon system in all conditions. At the NO3- addition groups, HCO3- and p (CO2) increase while pH and CO3(2-) decrease when the concentration of NO3- < or = 37.

[Variation characteristics and controlling factors of heavy metals in the South Yellow Sea surface seawaters].

Based on the 8 cruises data of surface seawater heavy metals and other related environmental factors from 1997 to 2004 of the South Yellow Sea (SYS), distribution patterns, mechanisms controlling the distributions and pollution levels of heavy metals (As, Cd, Cu, Hg, Pb, Zn) were studied with the data of 2003-10, and 8-year-fluctuation trends of heavy metals were also discussed. The average concentrations of heavy metals in surface seawater were 2.33, 0.