[Effects of chronic hypoxic hypercapnia on spatial learning-memory and expression of NMDAR1 in rats].

Aim: To explore the effect of chronic hypoxic hypercapnia on learning-memory and the possible mechanisms involved.

Methods: Fifty-eight male SD rats were randomly divided into three groups: Normal control group (NC, n=18), 2-week (2HH, n=18), and 4-week hypoxic hypercapnia (4HH, n=20) group. The rats, spatial learning-memory tasks were assessed by the Morris water maze.