A randomized controlled pilot trial of "Feiji Recipe" on quality of life of non-small cell lung cancer patients.

In order to pilot a study observing the feasibility of applying the Core Quality of Life Questionnaire (QLQ-C30) version 2.0 to assess the quality of life (QOL) of patients with NSCLC treated with Feiji Recipe, a randomized, parallel controlled clinical trial was conducted in the university-affiliated hospital. Seventy inpatients who met the inclusion criteria were randomized into the study, and 60 cases were available as subjects for QOL data analysis.

[Effects of Feiji Formula on lung cancer metastasis in mice].

Objective: To observe the effects of Feiji Formula, a compound traditional Chinese herbal medicine, on lung cancer metastasis in mice.

Methods: The lung cancer metastasis model of mice was established in this experiment study. Twenty-four mice were randomly divided into three groups: untreated group, cisplatin group and Feiji Formula group.

[Intervention effect of Feiji Recipe on immune escape of lung cancer].

Objective: To evaluate the intervention effect of Feiji Recipe (FJR) on tumor immune escape.

Methods: In the prospective randomized control study, 60 cases of middle stage and advanced non-small cell lung cancer (NSCLC) with qi-yin deficiency syndrome were randomly assigned to the treatment group and the control group, 30 in each group. The levels of CD+ CD25+ Tr, interleukin-10 (IL-10), vascular endothelial growth factor (VEGF), sCD44v6 and transforming growth factor-beta1 (TGF-beta1) of peripheral blood were observed before and after treatment, and the clinical efficacy of FJR was evaluated depending upon the changes in tumor size, Karnofsky Performance scoring (KPS) and TCM syndrome.

[Evaluation on effect of feiji recipe on quality of life of patients with non-small cell lung cancer by adopting international questionnaire of QOL].

Objective: To evaluate the effect of Feiji Recipe (FJR) on quality of life (QOL) of patients with non-small cell lung cancer (NSCLC).

Methods: One hundred and two patients with NSCLC were randomly assigned into 2 groups. The 61 patients in the combined treated group were given FJR and chemotherapy and the 41 patients in the control group were treated with chemotherapy alone.

[Study on the relationship among the international scales for quality of life evaluation in patients with lung cancer, the East Cooperative Oncology Group Status and Lung Cancer Symptoms Lists of TCM].

Objective: To investigate the relationship among international scales for quality of life (QOL), physical performance assessment and Lung Cancer Symptoms Lists of Traditional Chinese Medicine (LCSL) from the viewpoint of clinical observation.

Methods: QOL of 363 patients with lung cancer was estimated with two international scales, the European Organization for Research and Treatment of Cancer QOL Questionnaire LC-43 (EORTC QLQ-LC43) and the Functional Assessment of Cancer Therapy General and Lung (FACT-L). In the same time, scores calculated by Karnofsky Performance Status (KPS), East Cooperative Oncology Group Status (ECOG) and LCSL were recorded.