Emerging roles of hydrogen sulfide in colorectal cancer.

Hydrogen sulfide (HS), an endogenous gasotransmitter, plays a key role in several critical physiological and pathological processes in vivo, including vasodilation, anti-infection, anti-tumor, anti-inflammation, and angiogenesis. In colorectal cancer (CRC), aberrant overexpression of HS-producing enzymes has been observed. Due to the important role of HS in the proliferation, growth, and death of cancer cells, HS can serve as a potential target for cancer therapy.

Nuclear proteins and diabetic retinopathy: a review.

Diabetic retinopathy (DR) is an eye disease that causes blindness and vision loss in diabetic. Risk factors for DR include high blood glucose levels and some environmental factors. The pathogenesis is based on inflammation caused by interferon and other nuclear proteins.

Exploring the impact of hydrogen sulfide on hematologic malignancies: A review.

Hydrogen sulfide (HS) is one of the three most crucial gaseous messengers in the body. The discovery of HS donors, coupled with its endogenous synthesis capability, has sparked hope for the treatment of hematologic malignancies. In the last decade, the investigation into the impact of HS has expanded, particularly within the fields of cardiovascular function, inflammation, infection, and neuromodulation.

Hydrogen sulfide and its donors: Novel antitumor and antimetastatic agents for liver cancer.

Hepatocellular carcinoma (HCC) is the sixth most frequent human cancer and the world's third most significant cause of cancer mortality. HCC treatment has recently improved, but its mortality continues to increase worldwide due to its extremely complicated and heterogeneous genetic abnormalities. After nitric oxide (NO) and carbon monoxide (CO), the third gas signaling molecule discovered is hydrogen sulfide (HS), which has long been thought to be a toxic gas.

The Role of Hydrogen Sulfide in the Development and Progression of Lung Cancer.

Lung cancer is one of the 10 most common cancers in the world, which seriously affects the normal life and health of patients. According to the investigation report, the 3-year survival rate of patients with lung cancer is less than 20%. Heredity, the environment, and long-term smoking or secondhand smoke greatly promote the development and progress of the disease.

A new and facile nanosilver SPR colored method for ultratrace arsenic based on aptamer regulation of Au-doped carbon dot catalytic amplification.

Here, Au-doped carbon dots (CD) nanosols with good stability were prepared by hydrothermal reaction method. We found that CD can efficiently catalyze the nanoreaction of reducing AgNO by glucose, and at 420 nm，the reaction products of yellow spherical silver nanosol exhibit an intense surface plasmon resonance (SPR) absorption peak. The nucleic acid aptamers (Apt) can be adsorbed on the surface of carbon dots, so that their catalytic activity was suppressed, the nanosilvers were reduced, the solution color becomes lighter, and the Abs value was weakened.

[A Hydride Generation-Catalytic Resonance Rayleigh Scattering Method for Detection of Trace Arsenic].

Arsenic is a toxic metal element and the establishment of a highly sensitive and selective method for As has great significance to human health and environment protection. In sulfuric acid medium, As(Ⅲ) was reduced by NaBH4 to form AsH3 gas that was trapped by the Ce(Ⅳ)-I- catalytic absorption solution to cause Ce(Ⅳ) concentration decreased and As particle increased, which resulted in the resonance Rayleigh scattering (RRS) and fluorescence increased at 370 and 351 nm respectively. The increased RRS and fluorescence intensities were linear to As(Ⅲ) concentration in the range of 0.

[A Facile Nanogold Surface Plasmon Resonance Absorption Method for CO Tracing].

The detection of gas pollutants in atmosphere and indoor air is very important to human health and safety. Monoxide carbon (CO) is a common gas pollutant with high toxicity that mainly comes from the inadequacy oxidization of carbon such as oil, coal and petrol inadequacy combustion, auto-gas and some natural disasters whose limit value in air is lower than 6.0 mg·m-3 in the national standard.

[Determination of Trace Boron Based on Gold Nanorod Plasmonic Resonance Rayleigh Scattering Energy Transfer to the Coordinate].

B is a necessary trace element for human and animals, but the excess intake of B caused poison. Thus, it is very important to determination of B in foods and water. The target of this study is development of a new, sensitive and selective resonance Rayleigh scattering energy transfer (RRS-ET) for the determination of B.

[Fluorescence Determination of Trace Se with the Hydride-K13-Rhodamine 6G System].

Se is a necessary trace element for human and animals, but the excess intake of Se caused poison. Thus, it is very important to determination of Se in foods and water. The target of this study is development of a new, sensitive and selective hydride generation-molecular fluorescence method for the determination of Se.

[Resonance Rayleigh scattering determination of trace tobramycin using aptamer-modified nanogold as probe ].

Nanogold (NG) was prepared using NaBH4 reduction of HAuCl4. The NG was modified by the tobramycin-aptamer to obtain a stable Apt-NG probe for tobramycin. The three aptamers containing 15, 21 and 27 bases were examined, and results showed that the aptamer with 21 bases was best and was chosen for use.

[Resonance Rayleigh scattering determination of trace ozone based on the cationic surfactant association particles].

In the presence of pH 4.0 HAC-NaAC buffer solution, using H3BO3-KI (BKI) as absorption solution, O3 oxidized KI to produce I2, and it reacted with excess I- to form I3- that combined with the cationic surfactant (CS) such as cetylpyridinium chloride (CPCl), tetradecyl pyridinium bromide (TPB), cetyl trimethyl ammonium bromide (CTMAB), and tetradecyl dimethylbenzyl ammonium chloride (TDMAC) to produce stable (CS-I3)n association particles, which exhibited a strong resonance Rayleigh scattering (RRS) peak at 470 nm. Under the chosen conditions, as the concentration of O3 (C) increased, the concentration of I3- increased, and the RRS intensity at 470 nm (1470 nm) increased due to more association particles forming.

[DNAzyme cracking-nanogold resonance Rayleigh scattering spectral method for the determination of trace Cu2+].

In the condition of pH 7.0 HEPES buffer solution and 0.19 mol x L(-1) NaCl, the substrate strand DNA (SS) and the enzyme strand DNA (ES) hybridized into a double-stranded DNA (dsDNA) at 80 degrees C.

[Resonance scattering detection of trace Hg2+ using aptamer modified AuSe nanoalloy].

Under the condition of sodium citrate as stabilizer, the gold-selenium (AuSe) nano-alloy was prepared by sodium borohydride reduction procedure, and was modified by single-strand aptamer to obtain an aptamer nano-alloy probe (apta-AuSe) for Hg(II). In pH 6.8 Na2HPO4-NaH2PO4 buffer solution and in the presence of NaCl of 33 mmol L(-1), the Apta-AuSe probe is not aggregation.

[Resonance scattering spectral detection of trace K+ by aptamer-modified nanogold probe].

In pH 7.0 Na2HPO4-NaH2PO4 buffer solution, nanogold particles interacted with the aptamer to form a stable aptamer-nanogold complex that was not aggregation by NaCl. At 80 degrees C, K+ and aptamer folded to form a stable G-quadruplex that released nanogold particles, the uncombined nanogold particles aggregated to large nanogold clusters that caused the increase in resonance scattering (RS) intensity at 563 nm in high concentration of NaCl, and the laser scattering showed that the average diameter was 120 nm.

[Resonance scattering detection of trace Hg2+ using herring sperm DNA modified nanogold].

In pH 7.0 tris-HCl buffer solutions and in the presence of 0.017 mol x L(-1) NaCl, herring sperm DNA was combined with gold nanoparticles in size of 10 nm to form stable complex, and the NaCl did not cause the aggregation of the gold nanoparticles.

[Fluorescence analysis of trace glucose using glucose oxidase and horseradish peroxidase].

In acetate buffer solution and in the presence of glucose oxidase (GOD), glucose reduced the dissolved oxygen to form H2O2 that oxidized catalytically the excess KI to from I3- by horseradish peroxidase (HRP). The I3- combines respectively with rhodamine S (RhS), rhodamine 6G(Rh6G), butyl-rhodamine B(b-RhB) and rhodamine B(RhB) to form RhS-I3, Rh6G-I3, b-RhB-I3 and RhB-I3 associated particles that result in fluorescence quenching at 556, 556, 584 and 584 nm, respectively. Under the optimal conditions, the concentration of glucose in the range of 0.

[A new immuno-nanosliver resonance scattering spectral probe for assay of IgG].

Using tri-sodium citrate as reducer, stable silver nanoparticles the size of about 20 nm were prepared by the microwave high pressure procedure with simplicity and rapidity. At pH 9.0, sliver nanoparticle was used to label goat anti-human IgG (GIgG) to obtain an immuno-nanosilver resonance scattering spectral probe (AgGIgG) for IgG.

[Flame atomic absorption spectrometric determination of H2O2 using (Au) core (Ag) shell nanoparticles].

The 10 nm gold nanoparticles were prepared by Frens procedure. Using tri-sodium citrate as reducer of AgNO3, and 10 nm gold nanoparticles as seed, the (Au)core(Ag)shell nanoparticles the size of about 30 nm were prepared at 90 degrees C for 10 min. Then it was separated by centrifuge at 10000 r x min(-1) for 15 min to obtain pure (Au)core(Ag)shell nanoparticles.

[Fluorescence quenching assay of ultratrace horseradish peroxidase using rhodamine dye].

In acetate buffer solution, the reaction of H2O2 with KI was catalyzed by horseradish peroxidase (HRP) to form I3-. The I3- combined respectively with rhodamine S(RhS), rhodamine 6G(Rh6G), rhodamine B(RhB) and butyl-rhodamine B(b-RhB) to form RhS-I3, Rh6G-I3, RhB-I3 and b-RhB-I3 association particles, resulting in the fluorescence quenching at 580, 580, 554 and 554 nm, respectively. The effect of pH value, rhodamine dye concentration, KI concentration, H2O2 concentration, reaction temperature and time on the fluorescence quenching intensity (deltaF) of the four catalytic systems was considered respectively.

[Study on the energy transfer fluorescence quenching reaction of acridine orange-4-(2-pyridylazo) resorcinol-V(V) system and analytical application].

An energy transfer technique for 4-(2-pyridylazo) resorcinol (PAR)-vanadium(V) and acridine orange (AO) was studied, and the optimum conditions of energy transfer system were also experimented. It was found that in citrate-Na2 HPO4 buffer solution at pH = 5.5, energy transfers from AO to vanadium(V)-PAR complexes.

[Immune resonance scattering spectral analysis of fenvalerate].

In the pH 7.2 Na2HPO4-NaH2PO4 buffer solutions and in the presence of PEG-6000, fenvalerate (Fen) antisera was combined with Fen specifically, and aggregated to form immune complex particles that exhibited five resonance scattering peaks at 350, 390, 420, 440 and 480 nm respectively. The peak at 390 nm was the strongest and was chosen for use.

[Immunonanogold catalytic spectrophotometric determination of trace complement 3].

Gold nanoparticles about 10 nm in size were prepared by improved trisodium citrate reduction procedure, and were used to label goat anti-human C3 to obtain a sensitive spectral probe for complement 3 (C3) in the condition of pH 7.5. The immune reaction between nanogold-labeled C3 antibody (anti-C3) and the antigen C3 took place to form the nanogold immune complex in pH 5.