Tensile force produced by a lipoma in the masseteric space possibly causing hyperostosis of the angle of the mandible.

Background: A lipoma is a benign tumor which may occur in the adipose tissue of any part of the body. The tumor is most commonly found on the trunk and extremities. Although it is the most common tumor of mesenchymal origin in the head and neck, its incidence is relatively rare.

Designer self-assembling peptide scaffold stimulates pre-osteoblast attachment, spreading and proliferation.

A new peptide scaffold was made by mixing pure RADA16 (Ac-RADARADARADARADA-CONH2) and designer peptide RGDA16 (Ac-RADARGDARADARGDA-CONH2) solutions, and investigate any effect on attachment, spreading and proliferation of pre-osteoblast (MC3T3-E1). The peptides, RADA16 and RGDA16, were custom-synthesized. They were solubilized in deionized water at a concentration of 10 mg/ml (1% w/v), the RGDA16 peptide solution was mixed 1:1 with RADA16 solution and a new peptide solution RGDAmix was produced.

[Expression of c-fos, OPG, OPGL in rabbit mandibular distraction osteogenesis zone].

Objective: To evaluate the possible signal transduction mechanism of the mechanical stress induced by the distraction procedure in osteocytes.

Methods: An animal model of mandibular distraction osteogenesis in rabbits was established. The expressions of c-fos, OPG and OPGL were detected by ultrasensitive S-P immunohistochemical method.

Radiographic and surgical template for placement of orthodontic microimplants in interradicular areas: a technical note.

Purpose: In recent years, microimplants have gained popularity in orthodontics. Microimplants are primarily placed in complex sites where critical anatomic structures, such as roots of teeth, may be damaged, so precise surgical planning is required prior to placement. The goal of this report was to introduce a newly developed technique for the placement of microimplants in interradicular areas and evaluate its accuracy.

[Expression related to vascular endothelial growth factor C and induced nitride oxide synthesizase in lymph node micrometastasis of oral squamous cell carcinoma].

Objective: To investigate the relationship of vascular endothelial growth factor C (VEGF-C) and induced nitride oxide synthesizase (iNOS) expression in lymph node micrometastasis of oral squamous cell carcinoma.

Methods: Samples were obtained from 47 cases of oral squamous cell carcinoma and 15 cases with normal oral mucosa, VEGF-C and iNOS mRNA expression were detected by RT-PCR method. Lymph node micrometastasis of 10 normal lymph nodes and 355 lymph nodes from 47 cases of oral squamous cell carcinoma was detected with immunohistochemical reaction in cytokeratin antibody.

[Change in Toll-like receptor 4 expression on interstitial macrophages in acute lung injury].

Objective: To observe changes in the level of Toll-like receptor 4 (TLR4) mRNA and the expression of TLR4 protein in interstitial macrophages in serious thoracic injury.

Methods: A rat model of severe thoracic trauma was reproduced,then interstitial macrophages were isolated and collected by enzymatic digestion before and after trauma cultured. TLR4 mRNA and the expression of TLR4 protein were measured by Northern and Western blotting before trauma and 2, 4, 8, 16, 24 hours after trauma.

[The relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma].

Objective: To probe the relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma.

Methods: The microlymphatic vessel density was detected with enzyme histo-chemical method in 47 cases of oral squamous cell carcinoma and 10 cases of normal oral mucosa; 355 lymphnodes were detected with immunohistochemically using monoantibody AE3.

Results: The mean MLVD was 14.

[Effect of severe thoracic trauma combined with endotoxin challenge on phagocytosis function of alveolar macrophages and pulmonary interstitial macrophages].

Objective: To observe the difference of phagocytosis between alveolar macrophages and pulmonary interstitial macrophages, and to investigate their responses to severe thoracic trauma with or without lipopolysaccharide (LPS) challenge.

Methods: A rat model of severe thoracic trauma was reproduced by thoracic impact machine. The alveolar macrophages and interstitial macrophages were isolated before injury and at 2, 4, 8, 16, 24 hours after injury respectively.