Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib).

Feline calicivirus (FCV) is an important and highly prevalent pathogen of cats that causes acute infectious respiratory disease. Here it is shown in vitro that FCV induces the production of cyclooxygenase-2 (COX-2) through the MEK1-ERK1/2 signaling pathway. Screening of FCV proteins revealed that FCV non-structural protein VPg enhanced COX-2 mRNA expression and protein production in CRFK cells in a concentration-dependent manner.

Fine nursing intervention relieves the clinical symptoms and decreases the adverse events in acute alcoholism patients.

Objective: The purpose of this study is to explore the effect of fine nursing interventions on the clinical efficacy of acute alcoholism patients (AA).

Methods: A total of 100 patients with AA were included in the study. Among them, 51 patients who underwent fine nursing intervention were assigned to the research group (RG), and the remaining 49 patients were treated with routine nursing intervention and were assigned to the control group (CG).

[Construction of a landscaping-type wetland system for wastewater treatment construction of a landscaping-type wetland system for wastewater treatment and analysis of plant denitrifying effect].

A pilot landscaping-type wetland system for wastewater treatment was constructed by introduction of 15 selected ornamental plant species (including 4 terrestrial plant species). The pilot system consists of 2 sequenced treatment units and 12 sub-units, i.e.