Criminal behavior among persons with schizophrenia in rural China.

Objective: This study is to explore the prevalence and risk factors for self-reported criminal behavior among persons with schizophrenia in rural China.

Methods: We used data from a 14-year prospective follow-up study (1994-2008) of criminal behavior among a cohort (N=510) of persons with schizophrenia in Xinjin County, China.

Results: The rate of criminal behavior was 10.

No association between vitamin D receptor polymorphisms and coronary artery disease in a Chinese population.

The clinical features suggest that genetic factors may have a strong influence on susceptibility to coronary artery disease (CAD). The aim of this study was to investigate the association between FokI (rs2228570) and BsmI (rs1544410) of the vitamin D receptor (VDR) gene polymorphisms and patients with CAD in a Chinese population. One hundred and fifty-two CAD patients and 212 healthy controls were genotyped for the FokI and BsmI polymorphisms in VDR gene using polymerase chain reaction-restriction fragment length polymorphism.

[A forensic pathological study of eighty-two cases of adrenal hemorrhage].

Objective: To analyze the relationship between adrenal hemorrhage and the cause of death, age and gender.

Methods: Eighty-two cases of adrenal hemorrhage were statistically analyzed.

Results: Adrenal hemorrhage occurred mostly in cases of sudden death, infection, trauma and asphyxia.

[The expressions of HSP 70 mRNA and c-fos mRNA in the skeletal muscle and cardiac muscle of rabbits by electrocuted].

Objective: To study the changes of HSP 70 mRNA and c-fos mRNA expression and to find a method to differentiate antemortem from postmortem electrocution.

Methods: Fifteen New Zealand rabbits were randomly divided into three groups, the antemortem electrocution group, the postmortem electrocution group, and the control group. Each group consists of five rabbits.

[Correlation between postmortem intervals and the changes of electrical conductivity in vitreous humor in rabbits after death].

Objective: To investigate the correlation between postmortem interval (PMI) and the changes of electrical conductivity in vitreous humor in rabbits after death.

Methods: The changes of electrical conductivity in vitreous humor in rabbits were measured using the conductivity meter under 30 degrees C during 0-48 hours and 20 degrees C during 0-120 hours after death.

Results: Electrical conductivity in vitreous humor in rabbits increased gradually under 30 degrees C and 20 degrees C from 0 to 48 hours and from 0-120 hours after death.

[Scanning electron microscopic observation of erythrocytes and endothelial cells of electrified death rabbits].

Objective: To identify electrified death of animals without electric marks.

Methods: Two animal models (model A and model B) of electrified death without electric marks were established. Model A: right anterior limb and left hind limb of rabbits were soddened by 0.

[Expressions of GABA and GABA(A)R-alpha1 in the brain of rats poisoned by tetramine].

Expressions of GABA and GABA(A)R-alpha1 in the brain of rats poisoned by Tetramine were analyzed to explore the intoxication mechanism. Methods Sixty rats were randomly divided into control, sham poisoned, high-dose poisoned (1.0 mg/kg tetramine) and low-dose poisoned (0.

[Postmortem changes of liver phosphofructokinase-2 level in rats following different causes of death].

Objective: To study the changes of liver phosphofructokinase-2 (PFK-2) level at different postmortem intervals as well as due to different causes of death.

Methods: One hundred and five rats were randomly divided into 3 groups and the rats were sacrificed by either bleeding, suffocating, and neck breaking, respectively. The content of liver PFK-2 at 0, 1, 2, 4, 8, 12 and 24 hours following death were studied using immunohistochemishtry and image analysis.

[Advances of forensic entomology in China].

Forensic entomology is a branch of forensic medicine, which applies studies of insects and arthropods to getting evidence for court and has an analogous advantage in the estimation of the postmortem interval (PMI) and other questions of forensic relevance. The paper expounds its definition and contents and reviews some progress of the studies in some aspects in China such as the constitution and succession of insect community on the different cadavers, the applications of morphological features of insects and the technology of analysis of deoxyribonucleic acid (DNA) in forensic entomology, and forensic entomological toxicology etc.

[Relationship between CO II gene of mtDNA of Lucilia sericata and latitude interval].

Objective: To deduce the region that the geographical species of Lucilia sericata come from and determine the scene of crime (SOC) based on the gene analysis of mtDNA CO II.

Methods: A 635 bp region for CO II of 4 Lucilia sericata (belong to 2 geographical species) were collected and sequenced, compared with the data of GenBank. A neighbour-joining tree with the Tamura and Nei model was constructed by MEGA2.

[Contents of vitreous humor of dead body with different postmortem intervals].

Objective: To establish regression correlations between postmortem interval (PMI) and contents of human vitreous humor of dead bodies for forensic purposes.

Methods: The human vitreous humor were taken from 126 dead bodies between 0.5 to 216 hours after death, and 11 chemical elements were detected by the OLYMPUS AU400 auto-biochemistry instrument.

[Dynamic observation of brainstem auditory evoked potential and pathological changes of the brain after closed brain injuries in rats].

Objective: To investigate the dynamic experiences of pathological changes in brain and the injured role of brainstem auditory evoked potential (BAEP) after closed Mild Traumatic Brain Injury (MTBI) in rat.

Methods: A closed diffuse brain injury model was successfully produced in rat by hit the parietal bone with a spring-droved steel stick. The auditory brainstem response evoked by click at 50Hz stimulating frequency were recorded at pre-trauma, 15 min and 1, 3, 6, 12 h and 1, 2, 4, 7, 10, 14, 21 d after brain injury.

[Expressions of Bcl-2 and Caspase-3 in the internal organs of rats when tetramine was administered].

Objective: To find whether Bcl-2 and Caspase-3 take part in the pathophysiological mechanism of tetramine toxification.

Methods: Sixty Sprague-Dawley rats were divided into normal control group, the sham poisoned group, high dose poisoned group, low dose poisoned group. High dose poisoned group were administered 1.

[Advance of study on pathological mechanism of paraquat poisoning].

Paraquat which is used widely as a potent herbicide is poisonous, and its pathological mechanism is unclear. Studies show that it is so a strong oxidant that it can oxidate lipid and some enzyme, also, it can damage DNA directly or induce necrosis or apoptosis, which is marked in pulmonary. To offer new directions for treatment and studies on paraquat poisoning, this paper reviewed the foreign studies on mechanism of it.

[The relationship of injury timing with the change of neuronal apoptosis and the expression of caspase-3 after brain contusion].

Objective: To investigate and analyze the changes of neuronal-apoptosis and the expression of caspase-3 for finding out a new method of injury timing after brain contusion in human.

Methods: The tissue was stained by TUNEL for apoptosis and by immunohistochemistry for caspase-3. Image analysis technique was employed.

[A study on the expression of HSP70 in endothelial cells pretreated with ethanol and fluid shear stress].

Objective: To detect whether ethanol can affect the expression of HSP70 in endothelial cells under fluid shear stress.

Methods: Ethanol at different concentrations was added to the culture medium of endothelial cells, EA. Hy926, which was treated statically or under 1Pa fluid shear stress.

[The advances in the neuropathology of sudden infant death syndrome].

Sudden infant death syndrome is known as sudden death in 12 months postnatal without obvious cause, the cause of death and differential diagnosis of still couldn't be indefinite so far. In this paper, the recent studies on the SIDS neuropathology using immunohisto-chemical technology were reviewed in order to suggest the lethal patho-physiologic derangement or mechanism in SIDS involves dysfunction of sleep-related cardio-respiratory homeostatic controls or failure to arouse. Thus the main cause of SIDS lies in central nerve system, but not unique cause.

[Observation the electroporation of blood cells in vitro by scanning electron microscope].

Objective: To observe changes on cell membrane in blood cells after they were been electrified.

Methods: Blood were electrified for 5, 10, 20, 30 s, 1 min respectively, and Scanning electron microscope was used to detect the changes on their cell membranes.

Results: Pores were detected both on electrified erythrocytes and leukocytes with round or ellipse shapes.

[Relationship between the injury time and DNA fragmentation and its quantity in rat brain].

Objective: To observe the changes of DNA fragmentation and its quantity along with the time of injury in nerve cells after brain contusion.

Methods: The model of brain contusion caused by free drop hammer was established. TUNEL and Feulgen's DNA staining conjoined with image analysis technique were used for exploration.

[To estimate early postmortem interval by investigating changes of rats' gastrocnemius excitability].

Objective: To investigate the changes of excitability of rats' gastrocnemius after rats were died from mechanic asphyxia, so as to make an objective evidence for estimating of the early postmortem interval.

Methods: After rats were sacrificed by mechanic asphyxia, the reaction of rats' gastrocnemius to variable electric stimulation at different period after death were recorded by electricphysiological method.

Results: Changes in the properties of excitable tissue to electric stimulate in rats' gastrocnemius after mechanic asphyxia seems to be well correlated with the early postmortem interval and appeared a linear relation in certain period.

[Expression of c-fos protein after muscle contusion in experimental rats].

Objective: To study the relationship between the expression of c-Fos protooncogene and skeleton muscle contusion of rats, and to search for a sensitive marker of timing for skeleton muscle contusion.

Methods: Fifty Sprague-Dawley rats were randomly distributed into control group and experimental groups. The expression of c-fos was microscopically observed by immunohistochemical method.

[A study on expression of caspase-8 in organs of rats after electrical injury at antemortem or postmortem].

Objective: This study was conducted to detect the expression of caspase-8 in organs of rats after The electrical injury so as to elucidate whether caspase-8 is useful in identifying electrical lesion.

Methods: experiment included two parts. In the first part (the antemortem electrical injury part), thirty-five healthy male SD rats were randomly divided into seven groups (n = 5 per group), i.

[Change of brainstem auditory evoked potential with different stimulating frequencies after closed diffuse brain injuries of rat].

Unlabelled: OBJECTIVE To investigate the change of peak latency (PL), interpeak latency (IPL) and peak latency ratio (PL ratio) of brainstem auditory evoked potential (BAEP) with different stimulating frequencies after closed diffuse brain injuries of rat,and provide experimental evidence for clinical diagnosis of traumatic brain injury in early stage and also for Forensic practice.

Methods: A rat model for closed diffuse brain injury was successfully constructed by hit the parietal bone with a spring-driven steel stick. The auditory brainstem response (ABR) evoked by clicking with low stimulating frequency of 10 Hz and high stimulating frequency of 50 Hz were respectively recorded at 6 h, 12 h, 2 d, 4 d after brain injury.

[Expression of Cyt C in brain of rats poisoned by tetramine].

Objective: To investigate the evidence for the judgement on legal cases of intoxication by tetramine.

Methods: Fifty rats given tetramine by lavage were sacrificed at different time after intoxication. The expression of Cyt C was detected by immunohistochemistry, and the reasults were assessed by an image analysis system.

[Expression of c-Fos in rats organs after electrical injury].

Objective: To study the expression of c-fos in organs after rats electrified.

Methods: The brain, lung, heart, liver, spleen, kidney, muscle of electrified limb, and cutis of electrified limb of all experimental rats and those organs of control groups were dissected to detect the expression of c-fos by using immunohistochemistry staining, and the staining intensity were assessed by image analysis system.

Results: The expression of c-fos was observed in brain, heart, liver, lung, kidney and muscle in electrified directly group, the amount of expression reached peak at 2 h after electrified and decreasing at 8 h after electrified, and the expression showed faintness in electrified at the immediate after death group.