Publications by authors named "Zhi-Yu Feng"
[Effects of inhibiting the expression of lncRNA PVT1 on the proliferation, apoptosis and oxidative stress of vascular endothelial cells induced by hyperglycemia].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
September 2021
To investigate the effects of inhibition of lncRNA PVT1 on the proliferation, apoptosis and oxidative stress of vascular endothelial cells induced by hyperglycemic. Human umbilical vein endothelial cells (HUVECs) were cultured in vitro and divided into four groups: control group (5.5 mmol/L glucose), high glucose group (30 mmol/L glucose), high glucose + siNC group (30 mmol/L glucose +siNC, negative control group), HG + siPVT1 group (30 mmol/L glucose + siPVT1, lncRNA PVT1 silencing group).
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- The study aimed to explore how a decoction called NKETD affects the immune response in mice with Chronic Hepatitis B by measuring key immune markers like IFN-γ, IL-17A, and Treg cells.
- The researchers divided HBV transgenic mice into six groups to test different doses of the decoction and compare it with lamivudine and control groups, using ELISA and Flow Cytometry methods to analyze the results.
- Findings showed that NKETD increases IFN-γ levels and decreases IL-17A levels, with more significant effects at higher doses, suggesting that the decoction may effectively treat CHB by promoting Th1 and inhibiting Th17 responses, outperforming lamivudine in immune
Totally thoracoscopic closure for atrial septal defect on perfused beating hearts.
Eur J Cardiothorac Surg
June 2012
Objectives: To investigate the feasibility and safety of non-robotically assisted totally thoracoscopic closure for atrial septal defect (ASD) on perfused beating hearts.
Methods: Twenty-four patients (8-45 years, mean 14.4 ± 18.
Background: Quality of life in patients undergoing totally thoracoscopic closure of atrial septal defect is unclear.
Methods: Thoracoscopic atrial septal defect repair was performed in 96 patients (37 males, aged 19.4 ± 8.
Objectives: We sought to investigate the feasibility and safety of totally thoracoscopic repair of a ventricular septal defect.
Methods: Totally thoracoscopic repair of a perimembranous ventricular septal defect was performed in 36 patients (16 male patients; age, 5-19 years; average age, 10.2 ± 4.
Objective: The recent advent of robotically assisted surgery has enabled totally endoscopic repair of atrial septal defects and patent foramen ovale. This study investigates the feasibility and safety of totally endoscopic repair of an atrial septal defect through small incisions on the chest without robotic assistance.
Methods: Forty patients (23 female patients; average age, 15.