Publications by authors named "Zhi-Yong Zou"

Objective: Hypertriglyceridemic waist (HW), hypertriglyceridemic waist-to-height ratio (HWHtR), and waist-to-hip ratio (WHR) have been shown to be indicators of cardiometabolic risk factors. However, it is not clear which indicator is more suitable for children and adolescents. We aimed to investigate the relationship between HW, HWHtR, WHR, and cardiovascular risk factors clustering to determine the best screening tools for cardiometabolic risk in children and adolescents.

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Background: Evidence remains limited on the association between maternal ozone (O) exposure and congenital heart defects (CHDs) in offspring, and few studies have investigated the interaction and modification of paternal smoking on this association.

Methods: Using a sample including pregnant women at high risk of fetal CHD (with metabolic disease, first-trimester viral infection, family history of CHD, etc.) from a maternal-fetal medicine study covering 1313 referral hospitals in China during 2013-2021, we examined the associations between maternal O exposure during 3-8 weeks of gestational age and fetal CHD in offspring and investigated the interaction and modification of paternal smoking on this association.

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Unlabelled: The association between phthalates exposure and childhood abdominal obesity is still unclear. This study aimed to assess phthalates (PAEs) exposure level and explore the association between PAEs metabolites exposure and the risk of abdominal obesity in Chinese students aged 7-10 years. A total of 798 students aged 7-10 years were selected from the baseline survey of the cohort of Childhood Blood Pressure and Environmental Factors (CBPEF), which was established in Xiamen City, Fujian province, East China, from August to November in 2018.

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Background: Both caesarean section (CS) and lifestyle were linked with child adiposity. This study aimed to investigate whether CS delivery is linked with elevated risk of child adiposity regardless of a healthy lifestyle. Methods: All the subjects in this study came from a baseline survey of a national school-based program on healthy lifestyle interventions against adiposity among Chinese children and adolescents.

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To investigate whether a healthy lifestyle is associated with the lower childhood obesity regardless of birth weight. Participants were selected from a large-scale cross-sectional study conducted in the seven provinces across China. Birth weight and lifestyle factors were collected through a questionnaire.

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Objective: To evaluate the predictive performance of anthropometric indices for metabolic syndrome (MetS) among Chinese adolescents with different nutritional status.

Methods: We recruited 9,513 adolescents aged 10-18 years from seven provinces in China during September 2014. Anthropometric indices and blood pressure were measured at recruitment, and blood samples were collected for determining fasting plasma glucose and lipid profile.

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Background: The prevalence of metabolic syndrome (MetS) rapidly increased over the past decades. However, little evidence exists about the effects of long-term exposure to ambient air pollution on MetS in children and adolescents.

Objective: This study aims to assess the association between long-term ambient air pollution and the prevalence of MetS in a large population of Chinese children and adolescents.

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Article Synopsis
  • Previous research suggests green spaces can positively impact health, but studies on how school greenness affects children's obesity are limited.
  • This study examined the relationship between greenery around schools and body fat in over 56,000 Chinese children aged 6-18 using satellite data.
  • Findings indicated that increased school greenness was linked to lower body mass index (BMI) and waist circumference, with air pollution partially influencing this connection, but physical activity did not show a significant mediating effect.*
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Few studies have explored the links of air pollution and childhood lipid profiles and dyslipidemias. We aimed to explore this topic in Chinese children and adolescents. This study included 12,814 children aged 7-18 years who participated in a national survey in 2013.

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Atherosclerosis - the pathophysiological mechanism shared by most cardiovascular diseases - can be directly or indirectly assessed by a variety of clinical tests including measurement of carotid intima-media thickness, carotid plaque, -ankle-brachial index, pulse wave velocity, and coronary -artery calcium. The Prospective Studies of Atherosclerosis -(Proof-ATHERO) consortium (https://clinicalepi.i-med.

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Background: To quantify the association between effects of interventions on carotid intima-media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk.

Methods: We systematically collated data from randomized, controlled trials. cIMT was assessed as the mean value at the common-carotid-artery; if unavailable, the maximum value at the common-carotid-artery or other cIMT measures were used.

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Article Synopsis
  • Research shows a strong link between obesity and high blood pressure (BP), but how they are connected is still unclear.
  • The study involved 1,221 overweight or obese adults from Beijing, examining how inflammatory factors and adipokines influence this relationship, with a focus on differences between sexes.
  • Results indicated that in males, leptin influenced the connection between body fat and BP, while in females, hsCRP played a key role, highlighting the need for sex-specific approaches to managing obesity-related high BP.
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Article Synopsis
  • - The study investigated how birth weight (BW) affects the risk of metabolic syndrome (MetS) in adolescents and if maintaining a healthy body weight can lessen any negative effects associated with abnormal BW.
  • - Data from 6,206 Chinese adolescents aged 10 to 17 revealed that SGA adolescents with overweight or obesity had a 73% increased risk of MetS compared to those with appropriate BW, while normal-weight SGA adolescents did not show this increased risk.
  • - The results highlighted a significant difference in the percentage of MetS cases attributable to SGA (2.4%) versus overweight or obesity (44.2%), suggesting that achieving a healthy weight may mitigate the risks linked to low birth weight.
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We sought to identify the differences between adolescents left behind in their home villages/towns (LBA) and non-left behind adolescents (NLB) on subjective well-being and family functioning due to parental migration in south China. We used a stratified cluster sampling method to recruit middle school students in a city experiencing population-emigration in Jiangxi Province in 2010. Participants included adolescents from families with: (1) one migrant parent, (2) both parents who migrated, or (3) non-left behind adolescents (i.

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Stability of the intermediate frequency (IF) in the far-infrared polarimeter-interferometer diagnostic system is critically important for the long pulse discharge experiments on the EAST tokamak. In this note, a real-time remote/local IF stability control system is described. The measured plasma parameters, including the Faraday rotation angle, electron density, lower hybrid wave, and plasma current, are obtained with the aid of this newly developed IF stability control system.

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This paper proposed a method for rapid identification of rice storage period based on manifold dimensionality reduction algorithms and near infrared spectroscopy (NIRS) technique. The reflection spectrum curve of old rice and new rice were obtained with a field spectroradiometer and the acquired spectral data was preprocessed with direct orthogonal signal correction method (DOSC) to filter the independent signal from the spectral data which is irrelevant with the dependent variable Y array and eliminate the influence and interference of the irrelevant information in the following chemometric analysis. The Durbin-Watson test and Run test methods were utilized to detect the nonlinearity which exists in the spectral data structure.

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We aimed to examine the contribution of blood lipids to the association between BMI and blood pressure (BP) in children with overweight and obesity. Data were collected in elementary and high schools of Chaoyang District, Beijing, China in 2012. Participants' weight, height, BP and fasting plasma lipid profile were measured by standard protocols.

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Background: Although traditional Chinese medicine (TCM) is known as an integrative part of China's health care system, little is known on the prevalence and determinants of using TCM among the middle-aged and older Chinese population, especially among those with chronic conditions.

Methods: The nationwide survey data of 17,708 Chinese adults aged 45 and older from the China Health and Retirement Longitudinal Study were used to estimate the prevalence of TCM. SAS SURVEYLOGISTIC procedure was applied to identify factors associated with using TCM.

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Background: Self-reported diabetes has been found to be valid to evaluate people's diabetes status in the population of several countries. However, no such study has been conducted to assess the validity of self-reported diabetes in the Chinese population, the largest population with the highest rate of diabetes. The aim of our study is to evaluate the validity of self-reported diabetes among the middle-aged and older Chinese population.

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Purpose: To compare the 2-year effect of multiple doses of lutein/zeaxanthin on serum, macular pigmentation, and visual performance on patients with early age-related macular degeneration (AMD).

Methods: In this randomized, double-blinded, and placebo-controlled trial, 112 early AMD patients randomly received either 10 mg lutein, 20 mg lutein, a combination of lutein (10 mg) and zeaxanthin (10 mg), or placebo daily for 2 years. Serum concentration of lutein/zeaxanthin, macular pigment optical density (MPOD), visual functions including best-spectacle corrected visual acuity (BCVA), contrast sensitivity (CS), flash recovery time (FRT), and vision-related quality of life (VFQ25) was quantified.

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Article Synopsis
  • - The study aimed to determine how common arthritis is among middle-aged and older Chinese adults and to identify its risk factors.
  • - Using national survey data, researchers found that 31.4% of the population has arthritis, with increased prevalence in older age groups and higher rates in females compared to males.
  • - It was concluded that cardiovascular disease is a significant risk factor for arthritis, alongside other factors like age, gender, and physical activity.
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Article Synopsis
  • The study aimed to examine how lutein and zeaxanthin supplementation affects functional and macular pigment changes in patients with early age-related macular degeneration (AMD).
  • In a 2-year trial with 112 participants, those receiving various dosages of lutein or a combination with zeaxanthin showed significant increases in macular pigment optical density (MPOD) and retinal sensitivity compared to a placebo group.
  • The findings conclude that lutein and zeaxanthin supplementation can improve visual function and macular health in early AMD patients.
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Objective: To investigate the association between early age at menarche and blood pressure in Chinese girls aged 7 to 17 years.

Methods: A total of 76 869 girls aged 7 to 17 years old were selected from the national physical fitness and health research in 2010, and probit analyses were used to calculate the average age of menarche for each province. Girls whose age were lower than the P 10 of age at menarche were judged as early age at menarche, and matched with two selected participant without menarche based on the age and the same urban or rural areas.

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The aim of the present study was to evaluate the effects of lutein and lycopene supplementation on carotid artery intima-media thickness (CAIMT) in subjects with subclinical atherosclerosis. A total of 144 subjects aged 45-68 years were recruited from local communities. All the subjects were randomly assigned to receive 20 mg lutein/d (n 48), 20 mg lutein/d+20 mg lycopene/d (n 48) or placebo (n 48) for 12 months.

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Objective: This randomized controlled trial examined serum and macular (in vivo measured macular pigment optical density [MPOD]) responses to supplemental lutein and zeaxanthin in Chinese subjects with early age-related macular degeneration.

Methods: One hundred and eight patients with early age-related macular degeneration older than 50 y were randomized to low lutein (LL; 10 mg/d), high lutein (HL; 20 mg/d), lutein plus zeaxanthin (LZ; each 10 mg/d), or placebo during a 48-wk intervention. Serum concentrations were quantified by C(30) high-performance liquid chromatography (at baseline and 4, 12, 24, and 48 wk), and MPOD was measured by analysis of autofluorescence images (at baseline and 24 and 48 wk).

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