Publications by authors named "Zhi-Yong Lyu"
Background: () was a prevalent pathogenic bacterium among children. Due to the extensive use of antibiotics, the sensitivity of to these drugs has gradually declined. Since the 1960s, methicillin-resistant (MRSA) has emerged and spread worldwide, becoming a primary cause of both healthcare-associated (HA) and community-acquired (CA) infections.
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- Bloodstream infections (BSIs) in children are a significant concern, as they can lead to high morbidity and mortality, necessitating effective and appropriate treatment to avoid worsening antibiotic resistance.
- A comprehensive five-year study analyzed 2,544 bacterial strains from 2,368 pediatric BSI patients in Beijing, focusing on the species distribution and antibiotic resistance patterns.
- Results showed that gram-positive bacteria were the primary pathogens, with coagulase-negative staphylococci (CoNS) displaying high levels of antibiotic resistance, while common gram-negative bacteria also exhibited notable resistance to crucial antibiotics.