Publications by authors named "Zhi-Yan Lu"

Objectives: The clinical and imaging features of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 and symptomatic COVID-19 patients.

Methods: The clinical and chest computed tomography imaging data of 47 asymptomatic carriers and 36 symptomatic COVID-19 patients were derived. All patients underwent 4-6 CT scans over a period of 2-5 days.

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This study aimed to estimate the long-term trends of breast cancer incidence in Shanghai, Hong Kong, and Los Angeles (LA) Data were obtained from Cancer Incidence in Five Continents () database. The average annual percent change (AAPC) was conducted by joinpoint regression analysis, and the age, period and cohort effects were estimated by age-period-cohort (APC) analysis. The age-standardized incidence rates (ASIRs) in LA were higher than Shanghai and Hong Kong.

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Objective: To investigate the computed tomography (CT) characteristics and diagnostic value of novel coronavirus pneumonia (NCP or COVID-19) in pregnancy.

Methods: This study included ten pregnant women infected with COVID-19, treated in the Zhongnan Hospital of Wuhan University from January 20, 2020 to February 6, 2020. Clinical and chest CT data were collected and clinical symptoms, laboratory indicators, and CT images were analyzed to explore CT characteristics and diagnostic value for COVID-19 during pregnancy.

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Article Synopsis
  • The study investigates the link between MRI findings and clinical severity in patients with cryptococcal meningitis who do not have HIV, focusing on differences between immunocompetent and immunocompromised individuals.
  • A total of 65 patients were analyzed, revealing that those with underlying health issues experienced more severe symptoms, such as high neutrophil levels and increased cerebrospinal fluid cell counts.
  • Results indicated that patients with underlying diseases had more brain lesions and a greater correlation between the number of affected brain areas and cerebrospinal fluid characteristics.
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[Imaging findings and progress of schistosomal hepatopathy].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi

July 2017

Article Synopsis
  • Schistosomal hepatopathy is a common liver condition in China, with over 30,000 patients experiencing severe liver fibrosis reported in 2015.
  • The article discusses the various pathological signs, clinical symptoms, and imaging results related to schistosomal hepatopathy.
  • It focuses on the advancements in identifying typical imaging features of the disease and introduces new imaging techniques for assessing liver fibrosis.
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The aim of the present study was to observe the effects of a general extract of polysaccharides (LBPs) on methylmercury (MeHg)-induced damage in hippocampus neural stem cells (hNSCs). The hippocampal tissues of embryonic day 16 Sprague-Dawley rats were extracted for the isolation, purification and cloning of hNSCs. Following passage and proliferation for 10 days, the cells were allocated at random into the following groups: Control, LBPs, MeHg and MeHg + LBPs.

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Article Synopsis
  • A high-throughput screening system was developed to efficiently identify halophilic bacteria that can degrade phenol, replacing traditional methods that are less effective.
  • The system utilized 48 deep well microplates for bacterial cultivation and 96-well microplates for measuring phenol concentrations, streamlining the process.
  • The study identified Halomonas sp. strain 4-5 from a successful halophilic community, which could degrade over 94% of phenol in saline conditions while producing ectoine, with key functional genes involved in the degradation process detected through PCR.
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