Oral Surg Oral Med Oral Pathol Oral Radiol
August 2012
The solid variant of keratocystic odontogenic tumor is an extremely rare tumor. Its clinical and pathologic features remain poorly defined, even in the 2005 World Health Organization odontogenic tumor classification. We report an unusual lesion in a 38-year-old female Chinese patient.
View Article and Find Full Text PDFHua Xi Kou Qiang Yi Xue Za Zhi
December 2010
Tumors of synchronous benign and malignant in unilateral salivary glands have rarely been reported. A case of 21-year-old girl who was diagnosed as synchronously adenoid cystic carcinoma of the left parotid and pleomorphic adenoma of the left submandibular gland. The classification, clinic pathology, diagnosis, possible mechanism were discussed based on similar literatures.
View Article and Find Full Text PDFHua Xi Kou Qiang Yi Xue Za Zhi
April 2007
Objective: To investigate the effect of FAK on biological characteristics of tongue squamous cell carcinoma cell Tca8113.
Methods: Lipofect was used to transfect FAK into Tca8113 cell lines. The difference in expression of FAK between the transfected and non-transfected cell lines was detected by immunofluorescence assay.
Objective: To study the expression of P63 in human salivary gland development and the existing of salivary gland stem cells.
Methods: 24 embryonic salivary gland samples in different stage, 10 normal salivary gland samples were collected. HE-stained and immunochemistry stain were used.
Sichuan Da Xue Xue Bao Yi Xue Ban
November 2006
Objective: To study the correlation between expression levels of focal adhesion kinase (FAK) in oral squamous cell carcinoma (OSCC) and clinical prognosis with pathologic parameters.
Methods: Eighty paraffin embedded tissue specimens of OSCC were studied by immunohistochemistry. The data was analyzed by SPSS statistical software.
Objective: To detect the expression of deltaNp63 in human salivary gland tumor and analyze its role in the malignant salivary gland tumors.
Methods: Collecting the samples from 68 cases of pathologically proven salivary gland tumours and investigating the microscopic sections with HE stain and immunohistochemical-SP stain.
Results: It was found that the expression of deltaNp63 is gradually increased in the malignant tumours, the myoepithelial cells and the basal cells of the salivary gland tumors are positive, and the expression of deltaNp63 is correlated directly with benign and malignant tumor.
Zhonghua Kou Qiang Yi Xue Za Zhi
September 2005
Objective: To study the clinicopathological features and diagnostic criteria of Ewing's sarcoma/primitive neuroectodermal tumor (Ewing's sarcoma/PNET) in oral and maxillofacial region.
Methods: There were 15 patients with Ewing's sarcoma/PNET in the last 35 years at our hospital, aged 1-49 years and mean 14.5 years.
Hua Xi Kou Qiang Yi Xue Za Zhi
June 2004
Objective: To analyse the clinical and pathological characteristics of minor salivary gland tumors.
Methods: A retrospective analysis on 615 cases of intraoral minor salivary gland tumors from 1990-2002 with a confirmed pathologic diagnosis was carried out.
Results: In 615 cases of minor salivary gland tumors, 265 cases were benign, 350 cases malignant.
Objective: To explore the correlation between neck lymph node metastasis and matrix metalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas(OSCC).
Methods: Immunohistochemistry LsAB technique was used to observe the expression of MMP-2 at the invasive tumor front and center of OSCC, and the correlation between the expression of MMP-2 in OSCC and neck lymph node metastasis were respectively analyzed by statistics.
Results: The results demonstrated that MMP-2 existed in all 71 cases, which the expression of MMP-2 at the OSCC front was more significant than that of MMP-2 at the OSCC center (P < 0.
Zhonghua Kou Qiang Yi Xue Za Zhi
November 2003
Objective: To investigate the presence of HPV infection of oral mucosa proliferative lesions in children and determine the associations of HPV types with oral mucosa lesions in children.
Methods: Immunohistochemical method and in situ hybridization techniques were applied to detect human papillomavirus (HPV) infection in biopsies taken from clinical lesions in oral mucosa of 30 children.
Results: The most frequent lesions detected were SCP (66.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2002
Objective: To assess the treatment effect of sodium hyaluronate (HA) on experimental temporomandibular joint (TMJ) osteoarthritis of rabbits in comparison with prednisolone (PS).
Methods: The upper compartments of both TMJs of 12 Japanese White Ear Rabbits were injected with 0.2 ml of 1.