Publications by authors named "Zhi-Xian Zhong"
J Tradit Complement Med
November 2023
Article Synopsis
- Xianglian Wan (XLW) is a traditional Chinese medicine known for protecting digestive functions, and this study investigates its potential anti-colorectal cancer effects, specifically highlighting berberine as the active component.
- The research utilizes literature mining, bioinformatics, and experimental procedures to demonstrate how berberine regulates the ACC/FASN pathway, which is involved in lipid metabolism, and its ability to inhibit tumor growth in colorectal cancer.
- Findings reveal that berberine can significantly downregulate FASN and ACC expression in tumor tissues, suggesting that it inhibits colon cancer cell proliferation by interfering with lipid metabolism through this critical signaling pathway.
