Publications by authors named "Zhi-Wei Zhong"

Background: The hand skeletal features of children and adolescents at different growth statuses and development periods, and the correlation between these skeletal features and hand asymmetric force are currently unclear. Thus, this study sought to investigate the hand skeletal features of children and adolescents at different growth statuses and at different periods of development, and the correlation between these skeletal features and asymmetric force in hands.

Methods: A retrospective study was performed on subjects aged 4-20 years with good growth status (group A) or short stature (group B).

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Background: It is difficult to differentiate giant cell tumors of the bone (GCTB) from chondroblastoma around the knee based on imaging findings. This study analyzed the imaging features of these 2 diseases for better differentiation.

Methods: This retrospective cross-sectional cohort study reviewed data of patients with pathologically confirmed GCTB (n=81; age 15-75 years; median age 33 years) and chondroblastoma (n=18; age 12-34 years; median age 14 years).

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Objective: The objective of this study is to analyze the clinical and imaging features of desmoplastic fibroma of bone (DFB) for correct diagnosis.

Materials And Methods: Twenty patients with DFB confirmed by pathology were enrolled, and the imaging presentations were analyzed. Among 20 patients, plain X-ray was performed in all patients, computed tomography (CT) was performed in 12, and magnetic resonance imaging (MRI) was conducted on eight.

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Background: The scapula is a small irregular-shaped flat bone, which may suffer from a variety of tumors or tumor-like lesions. As the imaging manifestations are complex and changeable, correct imaging diagnosis is difficult.

Introduction: At present, there are few related radiology literatures, and it is necessary to fully analyze the imaging signs of different types of benign and malignant tumors in scapula to guide clinical treatment.

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Background: To investigate the imaging features of hemangiomas in long tabular bones for better diagnosis.

Methods: Twenty-four patients with long bone hemangiomas confirmed by pathology were enrolled. Nineteen patients had plain radiography, fourteen patients had computed tomography (CT) and eleven had magnetic resonance imaging (MRI).

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Introduction: In lumbar spinal stenosis, correlating symptoms and physical examination findings with decompression levels based on common imaging is not reliable. Paraspinal mapping (PM) and diffusion tensor imaging (DTI) may be possible to prevent the false positive occurrences with MRI and show clear benefits to reduce the decompression levels of lumbar spinal stenosis than conventional magnetic resonance imaging (MRI) + neurogenic examination (NE). However, they must have enough positive rate with levels which should be decompressed at first.

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Cyclin-dependent kinase 2 (CDK2) is a member of serine/ threonine protein kinases, which initiates the principal transitions of the eukaryotic cell cycle and is a promising target for cancer therapy. The present study was designed to inhibit cdk2 gene expression to induce cell cycle arrest and cell proliferation suppression. Here, we constructed a series of RNA interference (RNAi) plasmids which can successfully express small interference RNA (siRNA) in the transfected human cells.

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Article Synopsis
  • - The study assessed the effectiveness of MRI in diagnosing and staging cervical cancer in 72 patients, focusing on various tumor characteristics like size, location, and invasion.
  • - MRI successfully identified cervical cancer in 71 out of 72 cases, with 86% accuracy in locating tumors; however, its staging accuracy was lower at 64%.
  • - While MRI is good at detailing tumor size and invasion, especially regarding parametrial invasion, it is not reliable for diagnosing early-stage (IA) cervical cancer without additional clinical and cellular evaluations.
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Synopsis of recent research by authors named "Zhi-Wei Zhong"

  • - Zhi-Wei Zhong's research primarily focuses on the imaging and clinical features of various bone tumors, such as giant cell tumor, chondroblastoma, and desmoplastic fibroma, aiming to improve diagnostic accuracy and differentiation through comprehensive imaging analyses.
  • - His recent studies have explored the skeletal features in children and adolescents at different growth stages, investigating correlations between these features and hand asymmetry, thereby contributing to the understanding of developmental abnormalities.
  • - Zhong has also examined the effectiveness of advanced imaging techniques, such as paraspinal mapping and diffusion tensor imaging, in diagnosing conditions like lumbar spinal stenosis, suggesting potential improvements over traditional MRI approaches.