Background: Non-liquefied multiple liver abscesses (NMLA) can induce sepsis, septic shock, sepsis-associated kidney injury (SA-AKI), and multiple organ failure. The inability to perform ultrasound-guided puncture and drainage to eradicate the primary disease may allow for the persistence of bacterial endotoxins and endogenous cytokines, exacerbating organ damage, and potentially causing immunosuppression and T-cell exhaustion. Therefore, the search for additional effective treatments that complement antibiotic therapy is of great importance.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
February 2022
Objective: Stroke survivors are usually unable to perform activities of daily living (ADL) independently due to loss of hand functions. Soft pneumatic gloves provide a promising assistance approach for stroke survivors to conduct ADL tasks. However, few studies have explored effective control strategies for the 'human-soft robot' integrated system due to challenges in the nonlinearities of soft robots and uncertainties of human intentions.
View Article and Find Full Text PDFJ Stroke Cerebrovasc Dis
July 2021
Objectives: Soft robotic hands are proposed for stroke rehabilitation in terms of their high compliance and low inherent stiffness. We investigated the clinical efficacy of a soft robotic hand that could actively flex and extend the fingers in chronic stroke subjects with different levels of spasticity.
Methods: Sixteen chronic stroke subjects were recruited into this single-group study.
Front Bioeng Biotechnol
December 2020
Stroke has been the leading cause of disability due to the induced spasticity in the upper extremity. The constant flexion of spastic fingers following stroke has not been well described. Accurate measurements for joint stiffness help clinicians have a better access to the level of impairment after stroke.
View Article and Find Full Text PDFFront Bioeng Biotechnol
February 2020
Strokes cause severe impairment of hand function because of the spasticity in the affected upper extremities. Proper spasticity evaluation is critical to facilitate neural plasticity for rehabilitation after stroke. However, existing methods for measuring spasticity, e.
View Article and Find Full Text PDFIEEE Int Conf Rehabil Robot
June 2019
In this paper, we present the new personalized 3D printed soft robotic hand for providing rehabilitation training and daily activities assistance to stroke survivors. The Soft-Elastic Composite Actuator (SECA) on the robotic hand is direct 3D printed to accommodate with different finger sizes. Flexion and extension can be actively facilitated on the SECA using the same pressurizing source.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
August 2012
Objective: To understand the schistosome infection status of armed police officers and soldiers in endemic areas of the middle and lower reaches of the Yangtze River and the impact caused by the camp environment.
Methods: The inside and outside environments of camps were investigated and they were classified as Grade A, B and C according to scores. The levels of antibody to schistosome of the armed police officers and soldiers were tested with ELISA.
Asian Pac J Cancer Prev
January 2013
Aims: Primary hepatocellular carcinoma (HCC) is a common malignancy often related to hepatitis viral infection. Smad4 is known to mediate the TGF-β pathway to suppress tumorigenesis. However, the function of Smad4 in HCC is still controversial.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
April 2012
Objective: To investigate the prevalence of schistosomiasis in Armed Police Forces in marshland and lake regions so as to provide the evidence for policy-making of the disease control.
Methods: The different types of duty were selected by the stratified cluster random sampling method in endemic areas of marshland and lake regions, and the snail survey was conducted, and the infectious status and epidemic factors of officers and soldiers who served more than 2 years were investigated.
Results: The geographical features included the embankment type, island type and islet type, and the serological positive rates were 1.
Polyploidization is a basic feature of plant evolution. Nearly all of the main food, cotton and oil crops are polyploid. When ploidy levels increase, yields double; this phenomenon suggested a new strategy of rice breeding that utilizes wide crosses and polyploidization dual advantages to breed super rice.
View Article and Find Full Text PDFAim: To study the in vivo and in vitro metabolism and the effect of para-toluene-sulfonamide (PTS) on cytochrome P450 enzymes (CYP450).
Methods: Total CYP450 and microsome protein content were determined after iv pretreatment of rats with PTS. CYP-specific substrates were incubated with rat liver microsomes.
Most anticancer drugs are characterized by a narrow therapeutic index, wide inter-patient variability of pharmacokinetic parameters and high toxicity. The need for dose individualization of anticancer drugs is now well accepted. The strategies that can be employed for optimizing dosage regimen were reviewed.
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