[The protective effects of ischemic preconditioning on reperfusion injury of rat lung].

Aim: To investigate the effects of ischemic preconditioning on reperfusion injury of rat lung.

Methods: Rat isolated lungs (n=8 in each group) were stabilized and perfused by Krebs-Henseleit solution on a modified langendorff perfusion apparatus. 36 wistar rats were divided into three groups: ischemic preconditioning group, ischemia/reperfusion group and control group.

[Effect of NO on automaticity of rabbit sino-atrial node].

Aim: To investigate the effects of exogenous NO donors sodium nitroprusside (SNP) and 3-morpholinosydnonimine (SIN-1) on automaticity of the rabbit sino-atrial node in vitro and the action mechanism.

Methods: The intracellular microelectrode technique is used to record the action potentials of rabbit sino-atrial node and APA (amplitude of AP), V(max) (maximal rate of depolarization), VDD (velocity of diastolic depolarization), RPF (rate of pacemaker firing) are analyzed.

Results: SNP(10(-5) - 10(-2) mol/L) increased its RPF and VDD dose-dependently.