Publications by authors named "Zhi-Ping Liang"
Background: To determine the related imaging findings and risk factors to refracture of the cemented vertebrae after percutaneous vertebroplasty (PVP) treatment.
Methods: Patients who were treated with PVP for single vertebral compression fractures (VCFs) and met this study's inclusion criteria were retrospectively reviewed from January 2012 to January 2019. The follow-up period was at least 2 years.
Article Synopsis
- Whole-lesion ADC histogram analysis is emerging as a promising tool for distinguishing between benign and malignant breast lesions, but it isn't widely used yet in clinical settings.
- A meta-analysis of five studies with 493 patients found the pooled sensitivity to be 85% and specificity 79% for this analysis method, demonstrating its effectiveness in diagnosis.
- The study concludes that while ADC histogram analysis shows good diagnostic performance, further research is needed to confirm these findings due to the limited number of studies considered.
Gliomas are highly malignant tumors, the most common of which are astrocytomas. A growing number of studies suggest that dysregulation of miRNAs is a frequent event contributing to the pathogenesis of gliomas. In this study, we found that over-expression of miR-132 inhibited cell proliferation and migration and triggered apoptosis, while knockdown of miR-132 showed opposite effects.
View Article and Find Full Text PDFThe bed nucleus of the stria terminalis (BNST), a nucleus defined as part of the extended amygdala, is involved in the expression of anxiety disorders. However, the regulatory mechanisms of BNST inhibitory activity that is involved in anxiety are unknown. Here, we showed that blocking neuregulin 1 (NRG1)-ErbB4 signaling in the BNST of mice, by either neutralizing endogenous NRG1 with ecto-Erbb4 or antagonizing the ErbB4 receptor with its specific inhibitor, produced anxiogenic responses.
View Article and Find Full Text PDFBackground & Objective: Combined therapy has been advocated for modern tumor treatment; the combined target therapy is a valuable research direction. Based on the previous research of nasopharyngeal carcinoma (NPC) radioimmunotherapy, this experiment was designed to develop two immunoconjugates of the monoclonal antibody BAC(5):PYM-BAC(5) and (131)I-BAC(5), and to assess the inhibition effects of their combined treatment on the NPC CNE-2 cells cultured in vitro.
Methods: Dextran T40 was used as media to link PYM and BAC(5).