Publications by authors named "Zhi-Min Xie"
Article Synopsis
- This study evaluates the effectiveness and safety of Qingpeng ointment (QPO), a Tibetan remedy, for treating symptoms of acute gouty arthritis (AGA) in patients experiencing significant joint pain.
- Conducted as a randomized, double-blind, placebo-controlled trial, 203 participants with AGA received either QPO or a placebo for seven days, with joint pain and swelling being the primary outcomes measured.
- The results indicated that the QPO group had reduced joint pain and swelling compared to the placebo group, along with improved joint mobility, while some mild adverse events were reported among participants, mainly skin irritations.
Article Synopsis
- The study aimed to analyze DNA methylation profiles in the blood of patients with Sjögren syndrome and healthy controls to understand how certain genes contribute to the disease's progression.
- Researchers performed whole-genome bisulfite sequencing and conducted various analyses to identify differentially methylated regions (DMRs) and their biological significance.
- They discovered 322 DMRs linked to 162 genes, with certain genes like HLA class I, ADAR, and OAS2 showing differential expression, suggesting they could serve as potential biomarkers for diagnosing Sjögren syndrome and may inform future treatments.
Background: Acute gouty arthritis (AGA) is an inflammatory arthritis clinically characterized by severe pain, swelling, and restricted movement of joints, which may cause physical disability and decrease quality of life. The use of recommended first-line treatment agents for AGA may be limited by adverse events. There has been a traditional use of alternative therapies for AGA.
View Article and Find Full Text PDFTo date, there has been little study of comparison between picosecond 532 nm laser and 755 nm Q-switched Alexandrite lasers in the treatment of freckles. To evaluate the efficacy and safety of picosecond 532 nm laser (PS 532) and 755 nm Q-switched Alexandrite laser (QSAL) for treatment of freckles in a split-face manner. Eighteen patients with freckles were enrolled in the study.
View Article and Find Full Text PDFObjective: To provide evidence on the efficacy and safety of Chinese herbal medicine (CHM) as interventions for systemic lupus erythematosus (SLE).
Methods: Seven electronic databases, including the Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), Chinese Biomedical Literature Service System (SinoMed), Wanfang, Embase, and PubMed, were comprehensively searched, from their inception to August 16, 2020, for all randomized controlled trials (RCTs) that focused on CHM used alone or in combination with conventional medicine for SLE. Outcomes were SLE activity index (SLEDAI), traditional Chinese medicine symptom/syndrome score (TCMSS), dosage of glucocorticoids, main serological testing, and incidence of adverse events.
Patients with chromoblastomycosis (CBM) usually have a history of local skin damage related to outdoor activities, mainly manifested as chronic refractory proliferative pathologic changes. We report a case of a 56-year-old man with CBM, identified as Fonsecaea pedrosoi infection by fungal culture and gene sequencing. This patient was successfully treated with a regimen of oral itraconazole (ITZ) and terbinafine lasting 7 months.
View Article and Find Full Text PDFAn aminobenzanthrone Schiff base has been synthesized as a new fluorescence carrier for the preparation of an optical chemical sensor for iodine. The response of the sensor is based on fluorescence quenching of the aminobenzanthrone Schiff base by iodine. The sensor shows a linear response toward iodine in the range of 1.
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