Publications by authors named "Zhi-Lin Ma"
Background: Post-stroke depression (PSD) is one of the most common and serious sequelae of stroke. The pathogenesis of PSD involves both psychosocial and biological mechanisms, and aerobic exercise is a potential therapeutic target. We conducted an in-depth exploration of the protective mechanisms of aerobic exercise in a PSD mouse model.
View Article and Find Full Text PDFSeven isoprenylated flavonoids were isolated from Artocarpus styracifolius, including one new triisoprenylated flavone, styracifolin D (1,) and six known ones, artocarpone B (2), kuwanon C (3), 6-C-prenyl luteolin (4), albanin A (5), 2,4,2',4'-tetrahydroxy-3'-(3-methyl-2-butenyl)-chalcone (6), and 3'-[γ-hydroxymethyl-(E)- γ-methylallyl]-2,4,2',4'-tetrahydroxychalcone 11'-0-coumarate (7). The structures of these compounds were determined by analysis of their spectroscopic and mass spectrometric data. Of them, 3 and 5 exhibited inhibitory effects on cathepsin K with IC(50) values of 114.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore how the HPLC fingerprint chromatogram of hawthorn leaves relates to their ability to inhibit the respiratory burst in rat PMN cells.
- The researchers developed mathematical models to transform HPLC fingerprint data into bioactive fingerprints, allowing for the assessment of the leaves' effects.
- Results showed a strong correlation between predicted and actual activity of the samples, suggesting a new evaluative system for analyzing traditional Chinese medicine through fingerprint chromatograms.*
Objective: To compare the analytical method of LC-UV and LC-MS determination of major polyphenolic components in leaves of Crataegus L.
Methods: By high-performance liquid chromatography method with VWD and MSD, Lichropsher C18 column (250 x 4.6 mm I.