Publications by authors named "Zhi-Lian Rui"

Article Synopsis
  • - T2DM is a progressive condition characterized by insulin resistance and declining β-cell function, with research indicating that microRNA (miRNA) plays a significant role in treatment.
  • - The study investigates the specific miRNA-125b-5p's effects on pancreatic β-cell function and insulin sensitivity in T2DM mice, alongside the involvement of Dapper1 (DACT1) and the JNK signaling pathway.
  • - Results show that T2DM mice had lower β-cell function and insulin sensitivity, linked to reduced miR-125b-5p and increased DACT1 and JNK levels; enhancing miR-125b-5p can improve insulin sensitivity by inhibiting the JNK pathway and D
View Article and Find Full Text PDF

A meta-analysis was conducted to compare oxaliplatin-based with fluorouracil-based neoadjuvant chemoradiotherapy and adjuvant chemotherapy for locally advanced rectal cancer. MEDLINE, EMBASE and CENTRAL were systematically searched for relevant randomized controlled trials (RCTs) until January 31 2017. Review Manager (version 5.

View Article and Find Full Text PDF