Publications by authors named "Zhi-Jun Le"
Article Synopsis
- Nuclear receptors (NRs) are crucial transcription factors for the growth and development of the insect Lasioderma serricorne, but their specific functions in the molting process had not been systematically studied before this research.
- In this study, 16 NR genes were identified and analyzed, revealing distinct expression patterns during different life stages: larvae, adults, and prepupae, with high expression levels in epidermis, fat body, and foregut.
- RNA interference experiments showed that silencing 15 NRs led to severe disruptions in the transition between larva, pupa, and adult stages, causing high mortality rates and impairing the formation of new cuticles, ultimately affecting key processes like 20E synthesis and chitin metabolism necessary
The peptidoglycan recognition protein (PGRP), an important pattern recognition receptor of insects, is significant for reducing innate immunity and effective pest control. We cloned four PGRP genes (LsPGRP-LB, LsPGRP-LB1, LsPGRP-LE, and LsPGRP-SC2) from the cigarette beetle, Lasioderma serricorne (Fabricius), which encoded proteins of 216, 197, 317, and 190 amino acids, respectively. Three LsPGRPs were predominantly expressed in the larval and pupal stages, whereas LsPGRP-LE displayed high expression in adults.
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