4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo.

Astroglioma is the most common primary tumor in the central nervous system without effective treatment strategies. Temozolomide (TMZ) is a chemotherapeutic drug to treat astroglioma but exhibits low potency and has side effects. Therefore, there is an urgent need to develop new compounds to treat astroglioma.

Photoelectrochemical immunoassay of lipoprotein-associated phospholipase A via plasmon-enhanced energy transfer between gold nanoparticles and CdS QDs/g-CN.

A facile and feasible photoelectrochemical (PEC) immunoassay based on plasmon-enhanced energy transfer between gold nanoparticles (AuNPs) and CdS quantum dots (QDs)/g-CN nanosheets was developed for the ultrasensitive detection of lipoprotein-associated phospholipase A (Lp-PLA). To construct such a sensing platform, the immunosensor was prepared by immobilizing Lp-PLA on a CdS QDs/g-CN-modified electrode. A competitive-type immunoreaction was utilized for Lp-PLA detection, with AuNP-labeled anti-Lp-PLA antibody used as the competitor.