Publications by authors named "Zhi-Hao Zuo"

1,2-Dichloroethane (1,2-DCA), a widely utilized chemical intermediate and organic solvent in industry, frequently enters the environment due to accidental leaks and mishandling during application processes. Thus, the in-situ remediation of contaminated sites has become increasingly urgent. However, traditional remediation methods are inefficient and costly, while bioremediation presents a green, efficient, and non-secondary polluting alternative.

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Pervasive environmental contamination due to the uncontrolled dispersal of 2,4-dinitrotoluene (2,4-DNT) represents a substantial global health risk, demanding urgent intervention for the removal of this detrimental compound from affected sites and the promotion of ecological restoration. Conventional methodologies, however, are energy-intensive, susceptible to secondary pollution, and may inadvertently increase carbon emissions. In this study, a 2,4-DNT degradation module is designed, assembled, and validated in rice plants.

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2,4-Dinitrotoluene (2,4-DNT) as a common industrial waste has been massively discharged into the environment with industrial wastewater. Due to its refractory degradation, high toxicity, and bioaccumulation, 2,4-DNT pollution has become increasingly serious. Compared with the currently available physical and chemical methods, in situ bioremediation is considered as an economical and environmentally friendly approach to remove toxic compounds from contaminated environment.

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Article Synopsis
  • The long-used organic herbicide 2,4-D has led to significant environmental pollution and ecological issues, prompting the need for effective remediation methods.
  • Researchers engineered a strain of Escherichia coli with a complete degradation pathway for 2,4-D, allowing it to effectively break down the herbicide within hours and use it as its sole carbon source.
  • Genetic analyses and imaging techniques confirmed that the engineered bacteria not only degraded 2,4-D efficiently but also showed reduced damage compared to non-engineered strains, proving synthetic biology as a promising approach for environmental bioremediation.
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