Publications by authors named "Zhi-Hai Liu"

We report an experimental study of a 1D quintuple-quantum-dot array integrated with two charge sensors in an InAs nanowire. The device is studied by measuring double quantum dots formed consecutively in the array, and corresponding charge stability diagrams are revealed with both direct current measurements and charge sensor signals. The one-dimensional quintuple-quantum-dot array is then tuned up, and its charge configurations are fully mapped out with the two charge sensors.

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Ethnopharmacological Relevance: The emergence and spread of antibiotic resistance bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), urgently need to develop alternative strategies or novel antibacterial drugs. Coptis chinensis Franch., one ancient Chinese herb, has been widely used for the treatment of intestine disease, such as diarrhea.

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We report the realization of a coupled quantum dot (QD) system containing two single QDs made in two adjacent InAs nanowires. One QD (sensor QD) was used as a charge sensor to detect the charge state transitions in the other QD (target QD). We investigated the effect of the tunneling barrier asymmetry of the target QD on the detection visibility of the charge state transitions in the target QD.

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Background: To assess the feasibility and safety of tubeless video-assisted thoracoscopic sympathectomy (VATS) with a single 5 mm port under nonintubated, intravenous anesthesia with spontaneous ventilation in selected patients with primary palmar hyperhidrosis (PPH).

Methods: Adults (aged between 18 and 60 years) with moderate or severe PPH symptoms were enrolled. Demographic information and clinical data were obtained from 172 consecutive patients undergoing thoracoscopic surgery for PPH from March 2014 to December 2020.

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Article Synopsis
  • * In the study, specific alkaloids, particularly 6-ethoxysanguinarine (6-ES), showed strong antibacterial effects against Gram-positive bacteria, including MRSA, by disrupting its membrane and metabolic functions.
  • * 6-ES demonstrated additional benefits, such as reducing inflammation and promoting wound healing in MRSA-infected mice, indicating its potential as a new treatment option with various antibacterial properties.
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In the present work, the working state of the crane leg is analyzed and discussed, and its structure is optimized. SolidWorks software is used for modeling; ANSYS software is used for finite element analysis. First of all, the constrained finite element method (CFEM) is used to analyze the linear eigenvalue buckling and geometric nonlinear buckling of outriggers with different cross-section shapes.

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Quantum dots (QDs) made from semiconductors are among the most promising platforms for the development of quantum computing and simulation chips, and they have the advantages of high density integration and compatibility with the standard semiconductor chip fabrication technology compared to other platforms. However, the development of a highly tunable semiconductor multiple QD system still remains a major challenge. Here, we demonstrate the realization of a highly tunable linear quadruple QD (QQD) in a narrow bandgap semiconductor InAs nanowire via a fine finger gate technique.

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Dye-sensitized solar cells (DSSCs) have been widely investigated; however, the development of promising dye sensitizers is still appealing. In this work, we perform a detailed theoretical search for high-efficiency D-π-A organic dyes using density functional theory and time-dependent density functional theory calculations. Specifically, we perform geometric optimization, and electronic structure and absorption spectra calculations for isolated dyes for two thieno[3,2-b]benzothiophene π-spacer-based D-π-A organic dyes SGT129 and SGT130, which show significant efficiency difference, before and after binding to a TiO semiconductor.

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  • The study explores the energy spectrum and wave functions of a nanowire quantum dot under strong spin-orbit coupling, using both infinite and finite square well models.
  • Regardless of the finite square well height, it is found that there are always two bound states with different symmetries.
  • As the well height decreases, the position of the highest probability density for the first excited state shifts, while the ground state's maximum remains at the center, highlighting a critical height where the spin-orbit effect is maximized.
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We study the electric-dipole transitions for a single electron in a double quantum dot located in a semiconductor nanowire. Enabled by spin-orbit coupling (SOC), electric-dipole spin resonance (EDSR) for such an electron can be generated via two mechanisms: the SOC-induced intradot pseudospin states mixing and the interdot spin-flipped tunneling. The EDSR frequency and strength are determined by these mechanisms together.

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Background: The nervous system, through the vagus nerve and its neurotransmitter acetylcholine, can down-regulate the systemic inflammation in vivo, and recently, a role of brain cholinergic mechanisms in activating this cholinergic anti-inflammatory pathway has been indicated. Galanthamine is a cholinesterase inhibitor and one of the centrally acting cholinergic agents available in clinic. This study aimed to evaluate the effect of galanthamine on circulating tumor necrosis factor alpha (TNF-alpha) in rats with lipopolysaccharide-induced peritonitis and the possible role of the vagus nerve in the action of galanthamine.

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Objectives: To compare lung reaeration measured by bedside chest radiography, lung computed tomography, and lung ultrasound in patients with ventilator-associated pneumonia treated by antibiotics.

Design: Computed tomography, chest radiography, and lung ultrasound were performed before (day 0) and 7 days following initiation of antibiotics.

Setting: A 26-bed multidisciplinary intensive care unit in La Pitié-Salpêtrière hospital (University Paris-6).

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  • The study aimed to compare the effectiveness of two types of nebulizers, the Aeroneb Pro vibrating plate and the Atomisor MegaHertz ultrasonic nebulizer, in delivering the antibiotic ceftazidime to the lungs.
  • In vitro experiments measured particle size and in vivo tests on anesthetized piglets assessed lung tissue concentrations and external depositions of the drug after nebulization.
  • The results showed that both nebulizers produced similar particle sizes and lung concentrations of ceftazidime, suggesting that the vibrating plate nebulizer is a viable option for inhaled antibiotic therapy.
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Introduction: Early detection of pneumothorax in multiple trauma patients is critically important. It can be argued that the efficacy of ultrasonography (US) for detection of pneumothorax is enhanced if it is performed and interpreted directly by the clinician in charge of the patients. The aim of this study was to assess the ability of emergency department clinicians to perform bedside US to detect and assess the size of the pneumothorax in patients with multiple trauma.

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Objective: To investigate proliferation and differentiation of neural stem cells in adult rats after cerebral infarction.

Methods: Models of cerebral infarction in rats were made and the time-course expression of bromodeoxyuridine (BrdU), Musashi1, glial fibrillary acidic protein (GFAP), and neuronal nuclear antigen (NeuN) were determined by immunohistochemistry and immunofluorescence staining. BrdU and Musashi1 were used to mark dividing neural stem cells.

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  • The study aimed to understand how growth hormone (GH) influences NF-kappaB activity in neutrophils and its role in organ injury from lipopolysaccharide (LPS) in rats.
  • Male Wistar rats were treated with LPS and various doses of GH, and the effects on neutrophil activity and organ injury were measured through specific assays.
  • Results showed that GH increased harmful NF-kappaB activity and neutrophil sequestration, suggesting that GH treatment worsens LPS-induced organ injury rather than helping it.
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