Baicalin Plays an Anti-Osteosarcoma Role and Promotes Osteogenic Differentiation by Inhibiting NF-κB Signaling.

Background: Osteosarcoma (OS) is commonly recognized as a malignant cancer originating from bone-forming mesenchymal stem cells, comprising approximately 20% of sarcomas. Baicalin, a bioactive flavonoid glycoside isolated from , has been demonstrated to possess potent anti-inflammatory and neuroprotective properties.

Objective: To explore the potential mechanisms through which baicalin exerts anti-osteosarcoma effects and facilitates osteogenesis .

Anti-TGFβ-1 receptor inhibitor mediates the efficacy of the human umbilical cord mesenchymal stem cells against liver fibrosis through TGFβ-1/Smad pathway.

The aim of the current investigation was to evaluate the anti-fibrosis potential of human umbilical cord mesenchymal stem cells (hUC-MSCs) and further to explore some of its underlying mechanisms. Hepatic fibrosis mice model was induced by CCl. Liver function parameters in serum and fibrosis-associated markers in tissues were detected.

Interleukin-6 as a potential molecular target in esophageal squamous cell carcinoma.

Knowledge of potential tumor markers may improve chemotherapeutic efficacy. Interleukin-6 (IL-6) expression in local tumor tissues is associated with cancer progression and poor prognosis in variety of cancer types. The aim of the present study was to investigate the role and potential application of IL-6 in determining the prognosis of esophageal carcinoma.

Association between body mass index and erosive esophagitis: a meta-analysis.

Aim: To conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE) and body mass index (BMI).

Methods: We identified the studies using PubMed. Studies were selected for analysis based on certain inclusion and exclusion criteria.