[The expression of midkine in acute leukemia and its significance].

Objective: To analyze the expression of midkine (MK) gene in acute leukemia patients, and explore the relationship between the gene and leukemia.

Methods: The MK gene expression levels were detected by real-time quantitative RT-PCR (RQ-RT-PCR) in bone marrow (BM) of 181 acute leukemia (AL) patients and 31 normal controls.

Results: MK gene was expressed in all AL patients, normal controls and AL patients in complete remission (CR).