Publications by Zhi-Fan Hu

Publications by authors named "Zhi-Fan Hu"

J Ethnopharmacol

January 2024

Ulcerative colitis (UC) is a significant inflammatory bowel disease affecting the colon, and traditional remedies like Baitouweng decoction (BD) are being re-evaluated for their medicinal properties despite limited understanding of their mechanisms.
This study assesses the impact of BD on autophagy in DSS-induced colitis mice, focusing on its role in enhancing the colonic barrier through the AMPK/mTOR signaling pathway.
Results show that BD effectively alleviates colitis symptoms by improving body weight and colon length, reducing inflammation, and enhancing the intestinal barrier function.

- Zhi-Fan Hu's recent research primarily focuses on the therapeutic effects of traditional Chinese medicine, particularly Baitouweng decoction, in treating inflammatory bowel diseases such as ulcerative colitis.
- The study highlights how Baitouweng decoction facilitates the repair of the intestinal barrier in models of colitis, linking its effects to the regulation of autophagy through the AMPK/mTOR signaling pathway.
- Findings from this research contribute to the understanding of how traditional herbal remedies can be integrated into modern medical treatments for gastrointestinal disorders, emphasizing their potential role in public health.