Global Research Trends in Dental Stem Cells: A Bibliometric and Visualized Study.

Dental stem cells (DSCs) are mesenchymal stem cell-like populations with self-renewal and multidifferentiation potential. These cells have been studied in regenerative medicine and tissue engineering. Despite rapid progress in the past two decades, there has been no bibliometric analysis of DSC research.

[Cytotoxicity of a novel endodontic treatment material iRoot BP Plus to human gingival fibroblasts].

Purpose: To compare the cytotoxicity of a novel endodontic treatment material iRoot BP Plus and mineral trioxide aggregate (MTA) to human gingival fibroblasts in vitro.

Methods: Cultured human gingival fibroblasts were exposed to multiple concentrations of material elutes (no dilution, 1:2 dilution, and 1:5 dilution). The test material samples were immersed and incubated in the culture medium for 1, 3 or 7 days at 37 degrees centigrade.

Histologic comparison between platelet-rich plasma and blood clot in regenerative endodontic treatment: an animal study.

Introduction: In regenerative endodontic treatment (RET) for immature permanent tooth, better treatment results could be obtained by applying platelet-rich plasma (PRP) as the scaffold rather than the blood clot. The goal of this study was to compare the histologic differences between using PRP and blood clot in RET.

Methods: Three 6-month-old beagles each carrying 9 premolars with double root canals were randomly assigned to the PRP group, blood clot group, or negative control group.

Regenerative endodontic treatment of an immature permanent tooth at an early stage of root development: a case report.

Introduction: Regenerative endodontic treatment (RET) has been used in treating nonvital immature permanent tooth whose root formation ranged from approximately two-thirds of the full root length to almost completely developed root with open apex at least 1.1 mm in diameter according to the reported cases. However, this case report was to introduce RET in an affected tooth at an early stage of root development.

[Expression of β-catenin in the apical papilla and dental pulp tissues of human permanent teeth].

Purpose: The expression of β-catenin at the level of mRNA and protein in the apical papilla and dental pulp tissues of human permanent teeth were compared to explore the possible relationship between β-catenin and the development of pulp-dentin complex.

Methods: Forty-eight healthy permanent teeth in need of extraction for orthodontic treatment were obtained. The apical papilla and dental pulp tissues were isolated immediately when the teeth were extracted.