Publications by authors named "Zhi-Da Shen"

Article Synopsis
  • - Thrombus and restenosis are major issues after stent implantation, primarily due to traditional drugs like rapamycin hindering endothelial cell repair.
  • - Nitric oxide (NO) produced by endothelial cells helps improve vascular function and inhibits smooth muscle cell growth; thus, combining it with rapamycin could enhance stent effectiveness.
  • - The study developed a stent coating using SNAP as an NO donor, which showed improved endothelial recovery and reduced smooth muscle cell growth in cultured cells, indicating a potential solution to enhance stent performance.
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Aim: To clarify the effects of the xeroderma pigmentosum group D (XPD) Asp312Asn and Lys751Gln gene polymorphisms on the risk of esophageal cancer (EC).

Methods: A computerised literature search was conducted to identify the relevant studies from the PUBMED and EMBASE databases, reviews, and reference lists of relevant articles. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the associations between the XPD Asp312Asn and/or Lys751Gln polymorphisms and EC susceptibility.

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