Publications by authors named "Zhi-Cheng Jiang"
Topological materials have broad application prospects in quantum computing and spintronic devices. Among them, dual topological materials with low dimensionality provide an excellent platform for manipulating various topological states and generating highly conductive spin currents. However, direct observation of their topological surface states still lacks.
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- Renal cell carcinoma (RCC), particularly clear cell RCC (ccRCC), was the focus of a study analyzing single-cell RNA sequencing (scRNA-seq) data to understand how the tumor microenvironment (TME) connects with clinical outcomes and immunotherapy responses.
- Researchers identified three distinct differentiation subsets of ccRCC cells and categorized ccRCC samples into four molecular subtypes based on differentiation-related genes (DRGs), which correlated with patient prognosis and immune checkpoint gene expression.
- The study developed a prognostic risk signature (PRS) and an easy-to-use nomogram based on the PRS, enabling more accurate predictions of ccRCC patient outcomes and emphasizing the importance of TME evolution in treatment responses.