[Effects of Targeting lncRNA on the Invasion and Nude Mouse Tumorigenicity of Epithelial Ovarian Cancer Cells].

Objective: To explore the effects of shRNA-mediated downregulating lncRNA on the invasion,nude mouse tumorigenicity and snail expression of epithelial ovarian cancer SKOV3 cells.

Methods: The expression of lncRNA was detected by RT-PCR in SKOV3 cells. The shRNA targeting the lncRNA gene was cloned into RNA interference plasmid.

Staphylococcal enterotoxin B administration in pregnant rats alters the splenic lymphocyte response in adult offspring rats.

Background: Our previous study suggested that SEB exposure in pregnant rats could lead to the change of T cells subpopulation in both peripheral blood and thymus of the offspring rats. However, rarely is known about the influence of SEB exposure in pregnant rats on T cell subpopulation in the spleens of offspring rats.

Results: SEB was intravenously administered to the pregnant rats at gestational day 16 in this study.