Validity and Responsiveness of EQ-5D in Asthma: A Systematic Review and Meta-analysis.

Objective: We aimed to synthesize the evidence on the construct validity and responsiveness of the EQ-5D and compare them with asthma-specific health-related quality-of-life scales, to guide further research and clinical applications in asthma.

Methods: We searched key databases from inception to 1 June, 2024 and used the COnsensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) method to appraise the evidence. The effect size estimates were aggregated using the inverse variance method to evaluate the relative efficiency of EQ-5D measures against the Asthma Quality of Life Questionnaire (AQLQ) and/or its corresponding preference-based index, Asthma Quality of Life-5 Dimensions (AQL-5D).

Lived experience of patients with sleep apnea: a systematic synthesis of qualitative evidence.

Background: Sleep apnea (SA) is a prevalent chronic disease with significant morbidity that negatively impacts a patient's perception of health and quality of life (QoL).

Objective: This review synthesized qualitative evidence on the experiences of patients living with SA to understand the disease's impacts on QoL.

Methods: We performed a systematic review of qualitative studies and searched eight electronic databases from inception dates to 22 September 2020.