Publications by authors named "Zhi Wen Shi"
Article Synopsis
- Congenital malformations of the female genital tract (CM-FGT) involve abnormal development of reproductive organs and can also affect other systems, with no identified genetic causes until now.
- A comprehensive whole-genome sequencing study was conducted on 590 participants in China, discovering various genetic anomalies associated with CM-FGT, including novel variants and highlighting ASH1L as a key pathogenic gene.
- The study's findings enhance the understanding of the genetic factors contributing to CM-FGT and suggest potential for prenatal screening based on the identified spatiotemporal gene expression patterns during early uterine development.
Biodegradable Oxide Neuromorphic Transistors for Neuromorphic Computing and Anxiety Disorder Emulation.
ACS Appl Mater Interfaces
October 2023
Brain-inspired neuromorphic computing and portable intelligent electronic products have received increasing attention. In the present work, nanocellulose-gated indium tin oxide neuromorphic transistors are fabricated. The device exhibits good electrical performance.
View Article and Find Full Text PDFIntroduction: We aimed to determine the diagnostic criteria of myosteatosis in a Chinese population and investigate the effect of skeletal muscle abnormalities on the outcomes of cirrhotic patients.
Methods: Totally 911 volunteers were recruited to determine the diagnostic criteria and impact factors of myosteatosis, and 480 cirrhotic patients were enrolled to verify the value of muscle alterations for prognosis prediction and establish new noninvasive prognostic strategies.
Results: Multivariate analysis showed age, sex, weight, waist circumference, and biceps circumference had a remarkable influence on the L3 skeletal muscle density (L3-SMD).
Sarcopenia as a prognostic predictor of liver cirrhosis: a multicentre study in China.
J Cachexia Sarcopenia Muscle
December 2021
Background: Diagnostic criteria for sarcopenia have not been established in Chinese. This study established criteria based on the L3-skeletal muscle index (L3-SMI) and assessed its value for outcomes predicting in cirrhotic Chinese patients.
Methods: Totally 911 subjects who underwent a CT scan at two centres were enrolled in Cohort 1 (394 male and 417 female subjects, aged 20-80 years).
Background & Aims: The EncephalApp Stroop test is a high-sensitivity but low-specificity test that has been used to identify patients with covert hepatic encephalopathy (CHE). We aimed to develop a new strategy to detect CHE, combining EncephalApp Stroop test score with scores from subtests of the psychometric hepatic encephalopathy scoring system (PHES).
Methods: We performed a survey of 569 adult volunteers (229 men) in 9 communities in Shanghai, China, administering the EncephalApp Stroop test to determine the range of scores in the general population.