Publications by authors named "Zhi Ling Wang"

Aims And Objectives: This study aimed to investigate the effectiveness of applying a multiphase optimization strategy (MOST) to enhance recovery after surgery (ERAS) protocols within the nursing management of children undergoing day surgery for snoring disease.

Background: While MOST has been applied to behavioral intervention research in smoking cessation, AIDS management, and weight loss by international scholars, its application in constructing nursing intervention projects remains relatively unexplored.

Design: Using convenience sampling, randomised controlled trial.

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Objective: To analyze the relationship between serum cystatin C (CysC), β-microglobulin (β-MG) and the efficacy of demethylation therapy in patients with acute myeloid leukemia (AML).

Methods: A prospective cohort study was conducted on 98 AML patients admitted to the Affiliated Hospital of Inner Mongolia Medical University from February 2019 to January 2022. All patients were treated with decitabine (DAC) + HAG regimen, 28 days as a course and treated for 3-4 courses.

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Background: For children with abdominal Henoch-Schonlein purpura presenting abdominal pain as an initial symptom and severe clinical manifestations, but without purpura appearance on the skin, the diagnosis and treatment are relatively difficult. This study summarized the characteristics of this group of patients by literature review and provided additional references for further refinement of glucocorticoid therapy in this vasculitis.

Case Summary: A 6-year-old girl presented mainly with repeated abdominal pain and had received short-term out-of-hospital treatment with hydrocortisone.

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In this study, we introduce an arthroscopic technique for posterior-superior capsular fenestration and spinoglenoid cyst resection completely via a trans-rotator cuff approach. This approach can provide a full field of view and allow evaluation of the scope of the cyst under direct vision, which reduces the risk of recurrence and injury to the suprascapular neurovascular bundle.

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Background: Back muscle injury is the most common illness involved in aged people. Muscular satellite cells, playing a key role in the muscle repairing process, are gradually losing their regenerative ability with aging, which attenuates the injured muscle repairing process. Electroacupuncture at Weizhong acupoint has been widely used in the treatment of young and aged patients with back muscle damage.

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Introduction: Collagen colitis (CC) is a microscopic colitis diagnosed by mucosal biopsy and is extremely rare in children.

Patient Concerns: We reported a child with severe persistent diarrhea that could not be relieved with traditional diarrheal treatment. No abnormalities were found after multiple colonoscopies.

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The present study is aimed to assess the safety and efficacy of steroid withdrawal or avoidance (SWA) in high-risk kidney transplant (HRKT). We performed a systematic review of the literature and pooled analysis of the available data concerning SWA following HRKT. HRKT is associated with patients undergoing repeat kidney transplantation, in African American recipients, or in patients with panel-reactive antibody levels >20%.

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Thiamine pyrophosphokinase (TPK) converts thiamine (vitamin B) into thiamine pyrophosphate (TPP), an essential cofactor for many important enzymes. TPK1 mutations lead to a rare disorder: episodic encephalopathy type thiamine metabolism dysfunction. Yet, the molecular mechanism of the disease is not entirely clear.

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Article Synopsis
  • The study aimed to identify risk factors for residual lesions and recurrence in high-grade cervical intraepithelial lesions (HSIL) patients with positive margins after undergoing cervical conization.
  • It analyzed data from 218 patients who underwent either cold knife conization (CKC) or loop electrosurgical excisional procedure (LEEP) from 2013 to 2016, finding significant correlations between factors like age, menopausal status, and HPV infection with residual disease rates.
  • The study concluded that while LEEP and CKC are equally effective regarding recurrence rates, HPV infection and glandular involvement were significant factors in recurrence, suggesting further research is necessary to validate these findings.*
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Objective: To summarize the clinical features of Enterococcus faecium meningitis in children.

Methods: The clinical data of nine children with Enterococcus faecium meningitis were analyzed.

Results: In all the nine children, Enterococcus faecium was isolated from blood, cerebrospinal fluid, or peripherally inserted central catheters; 6 (67%) patients were neonates, 2 (22%) patients were younger than 6 months, and 1 (11%) patient was three years and four months of age.

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Article Synopsis
  • The study aimed to explore how supplementation affects the gut microbiome and immune system development in neonatal mice by dividing 30 pregnant BALB/c mice and their offspring into three intervention groups and one control group.
  • The intervention groups consisted of different supplementation strategies for both mothers and their offspring, followed by analysis of the offspring’s stool samples to assess intestinal flora and immune response markers like immunoglobulin A (sIgA) and various cytokines.
  • Results showed significant shifts in the gut bacteria composition of supplemented groups compared to the control, including decreased and increased colony counts of specific bacterial species, but no significant differences in immune system markers between groups.
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The aim of the present study was to elucidate the effects of blocking the calcium signaling pathway of astrocytes (ASs) on oxygen and glucose deprivation (OGD)‑induced AS injury. The association between the changes in the concentrations of AS‑derived transmitter ATP and glutamic acid, and the changes in calcium signaling under the challenge of OGD were investigated. The cortical ASs of Sprague Dawley rats were cultured to establish the OGD models of ASs.

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Objectives: To investigate clinical features in infants of breast milk allergy(BMA), and the possible relationship with the changes of somatostatin (SST) and motilin (MTL) in breast milk.

Methods: Twenty three cases of pure breast feeding infants with allergic gastroenteritis were collected, while another 23 normal infants with pure breast feeding were enrolled as normal controls. Samples of infant stools and breast milk were collected for the measurement of SST and MTL levels detected by by radioimmunity.

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Objectives: To investigate the clinical features of viral encephalitis in children at acute stage, and the relationship of these clinical features with post viral encephalitic epilepsy.

Methods: The children with viral encephalitis treated in West China Second University Hospital between January 2010 and January 2014 were enrolled. The clinical features included general conditions, clinical manifestations, video electroencephalogram (VEEG), neuroimaging, virology, prognosis and antiepileptic drugs.

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Shenqi Fuzheng injection is extracted from the Chinese herbs Radix Astragali and Radix Codonopsis. The aim of the present study was to investigate the neuroprotective effects of Shenqi Fuzheng injection in cerebral ischemia and reperfusion. Aged rats (20-22 months) were divided into three groups: sham, model, and treatment.

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Objective: To identify the effects of ingested anti-rotavirus immunoglobulin on enteric expressions of SIgA in pediatric rotavirus enteritis.

Methods: In this randomized, placebo controlled clinic trial, 100 patients of pediatric rotavirus enteritis who simultaneously received fluid replacement as basic therapy, were randomly divided into control and immunoglobulin treated groups. The patients in experimental group were given "ingested antirotavirus IgY".

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Article Synopsis
  • The study aimed to compare the effectiveness of probiotics and oral immunoglobulin in treating pediatric rotavirus enteritis in 150 children.
  • The results showed that probiotics helped reduce intestinal imbalances and stool frequency but did not significantly speed up recovery, while oral immunoglobulin led to faster symptom relief and overall shorter disease duration.
  • Ultimately, probiotics are beneficial for preventing complications, but oral immunoglobulin acts more quickly and effectively against the virus itself.
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Objective: To accurately calculate the protein requirements in Chinese young adults using the indicator amino acid oxidation technique.

Methods: Nine women and ten men received a restricted daily level of protein intake (0.75, 0.

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Article Synopsis
  • - The study investigates the connection between Helicobacter pylori (H. pylori) infection and Henoch-Schonlein purpura (HSP) in Chinese children, noting that H. pylori is prevalent in China and associated with both gastric and potential systemic diseases.
  • - A meta-analysis reviewed ten studies, focusing on the prevalence of H. pylori in children with HSP (749 cases) compared to controls (560 cases), revealing that 49.27% of HSP children had H. pylori, significantly higher than the 23.39% in controls.
  • - The analysis determined a strong association between H. pylori infection and HSP, with a pooled odds ratio of 3.80
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A family of light rare earth complexes, [RE(acac)(3)(dpq)] (RE=La (1), Ce (2), Pr (3), Nd (4), Sm (5)) and [RE(acac)(3)(dppz)].CH(3)OH (RE=La (6), Ce (7), Pr (8), Nd (9), Sm (10) viz. acetylacetonate (acac), dipyrido[3,2-d:20,30-f]quinoxaline (dpq), dipyrido[3,2-a:20,30-c] phenazine (dppz)), have been synthesized and structurally characterized.

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Objective: To improve the understanding in pathology and provide steady proof for diagnosis and treatment of tethered cord syndrome (TCS), the ultrastructure of filum terminale (FT) with TCS will be researched, respectively.

Methods: Thirty-one fila were sectioned and divided into two groups according to diameter. Twenty-two fila thicker than 2 mm were placed into group 1; nine no thicker than 2 mm were placed into group 2.

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Objective: To investigate the changes of TrkB and Ras-MAPK in brain-derived neurotrophic factor (BDNF) protecting the embryonic rat cerebral cortical neurons against hypoxia-induced neurotoxicity.

Methods: The immunofluorescence technique, laser scanning confocal microscope and half-quantitative analysis were done to explore the changes of the intracellular levels of tyrosine kinase B (TrkB), phosphorylated TrkB and the mitogen-activated protein kinase (MAPK) in rat embryonic cortical neurons cultured in different time groups of hypoxia with or without BDNF pretreatment.

Results: The fluorescent intensity of TrkB and phosphorylated TrkB in the cytoplasm and the fluorescent intensity of MAPK in both cytoplasm and cell nucleus of the neurons were significantly increased in the presence of BDNF (P < 0.

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Article Synopsis
  • The study investigates the roles of two proteins, Bcl-2 and Bax, in liver injury caused by immune responses in rats, focusing on how reduced serum iron levels affect their expression and associated liver damage.
  • 48 male Wistar rats were divided into groups to create a model of low iron and immunological liver injury, measuring various factors like serum iron concentrations, liver enzyme activity, and protein expression.
  • Results showed that Bax expression significantly increased in liver injury models, while Bcl-2 levels remained unchanged, and inducing low iron conditions decreased the severity of liver damage compared to those without lower iron levels.
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Objective: To observe the pathological changes of fetal rat brain cells caused by transient intrauterine ischemia in pregnant rats.

Methods: The uterine arteries of the pregnant rats at 17 days of gestation were clamped for 30 min in the experimental group, the samples were collected 24, 48 and 72 hours respectively after the clamping of artery, respectively. In control group, the pregnant rat's abdomens were cut open and closed but the uterine arteries were kept intact; the samples were collected 24, 48 and 72 hours after the sham operation, respectively.

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