Numerical Study of the Microflow Characteristics in a V-ball Valve.

V-ball valves are widely applied in many process industries to regulate fluid flow, and they have advantages of good approximately equal percentage flow characteristics and easy maintenance. However, in some applications, the V-ball valve needs to have good performance under both large and extremely small flow coefficients. In this paper, the improvement of the original V-ball valve is made and the flow characteristics between the original and the improved V-ball valve are compared.

Fluid-Structure Interaction Analysis on Membrane Behavior of a Microfluidic Passive Valve.

In this paper, the effect of membrane features on flow characteristics in the microfluidic passive valve (MPV) and the membrane behavior against fluid flow are studied using the fluid-structure interaction (FSI) analysis. Firstly, the microvalve model with different numbers of microholes and pitches of microholes are designed to investigate the flow rate of the MPV. The result shows that the number of microholes on the membrane has a significant impact on the flow rate of the MPV, while the pitch of microholes has little effect on it.

Cavitation Suppression of Bileaflet Mechanical Heart Valves.

Purpose: Mechanical heart valves (MHVs) are widely used to replace diseased heart valves, but it may suffer from cavitation due to the rapid closing velocity of the leaflets, resulting in the damage of red blood cells and platelets. The aim of this study is to apply computational fluid dynamics (CFD) method to investigate the cavitation in bileaflets mechanical heart valves (BMHVs) and discuss the effects of the conduit and leaflet geometries on cavitation intensity.

Methods: Firstly, CFD method together with moving-grid technology were applied and validated by comparing with experimental results obtained from other literature.

Effects of throttling window on flow rate through feed-water valves.

Feed-water valves are widely used in nuclear power plants to regulate the flow rate of the water supplying to steam generators, and thus holding the water level in steam generators at desired values. The flow rate characteristics of feed-water valves have important effects on the management quality of the water level in steam generators and therefore influence the safety and the efficiency of nuclear power plants. In this paper, the effects of throttling window shapes on the flow rate characteristics through feed-water valves are investigated in two aspects, the overall performances and the fluid dynamics.

Actuation Mechanism of Microvalves: A Review.

The microvalve is one of the most important components in microfluidics. With decades of development, the microvalve has been widely used in many industries such as life science, chemical engineering, chip, and so forth. This paper presents a comprehensive review of the progress made over the past years about microvalves based on different actuation mechanisms.

SXBX pill suppresses homocysteine-induced vascular smooth muscle cells dedifferentiation by inhibiting NLRP3 inflammasomes activation via ERK/p38 MAPK pathways.

The dedifferentiation of vascular smooth muscle cells (VSMCs) is a key event in the pathogenesis of vascular remodeling-related disease. The present study aimed to investigate the effects of shexiangbaoxin (SXBX) pill, a traditional Chinese medicinal formula on VSMCs dedifferentiation and its potential mechanisms. High-fat diet (HFD) was introduced to lipoprotein receptor-deficient (LDLR) mice to generate hyperhomocysteinemia (HHcy), and plasma Hcy and lipid levels were analyzed.

Cavitating Flow through a Micro-Orifice.

Microfluidic systems have witnessed rapid development in recent years. As one of the most common structures, the micro-orifice is always included inside microfluidic systems. Hydrodynamic cavitation in the micro-orifice has been experimentally discovered and is harmful to microfluidic systems.