Publications by authors named "Zhezhen Wei"

The ever-growing challenges of traditional antibiotic therapy and chronic wound healing have created a hot topic for the development and application of new antimicrobial agents. Silver nanoclusters (Ag NCs) with ultrasmall sizes (<2 nm) and antibacterial effects are promising candidates for next-generation antibiotics, particularly against multi-drug resistant strains. However, the biosafety in the clinical application of Ag NCs remains suboptimal despite some existing studies of Ag NCs for biomedical applications.

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Multimodal tumor therapy with nanotechnology is an effective and integrative strategy to overcome the limitations of therapeutic efficacy and possible side effects associated with monotherapy. However, the construction of multimodal treatment nanoplatforms often involves various functional components, leading to certain challenges, such as time-consuming synthesis processes, low product yield, and inadequate biocompatibility. To address these issues, we have developed a straightforward method for preparing ultrathin CuS nanosheets (NSs) with surface defects for photothermal/photodynamic/chemodynamic therapy.

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Elucidating the structure-property relationships of ultra-small metal nanocluster with basic nuclear is of great significance for understanding the evolution mechanism in both the structures and properties of polynuclear metal nanoclusters. In this study, an ultra-small copper hydride (CuH for short) nanocluster was simply synthesized with high yield, and the large-scale preparation was also achieved. Single crystal X-ray diffractometer (SC-XRD) analysis shows that this copper NC contains a tetrahedral Cu core co-capped by four PPhPy ligands and two Cl in which the existence of the central H atom in tetrahedron was further identified experimentally and theoretically.

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