Global research trends and hotspots on human intestinal fungi and health: a bibliometric visualization study.

Background: This article employs bibliometric methods and visual maps to delineate the research background, collaborative relationships, hotspots, and trends in the study of gut fungi in human diseases and health.

Methods: Publications related to human gut fungi were retrieved from the Web of Science Core Collection. VOSviewer, CiteSpace, R software and Microsoft Excel were employed to generate visual representations illustrating the contributions made by countries/regions, authors, organizations, and journals.

[Observation of acupoint application of gel plaster on insomnia].

Objective: To observe the effect of acupoint application of gel plaster on quality of sleep and life in patients with insomnia.

Methods: A total of 63 patients with insomnia were randomized into a gel plaster group (32 cases, 1 case dropped off) and a placebo plaster group (31 cases). Acupoint application of gel plaster was applied at Yintang (GV 29) and Yongquan (KI 1) in the gel plaster group, placebo plaster was applied at the same acupoints in the placebo plaster group.

Nighttime safety evaluation for signalized intersections at the signal cycle level based on rear-end conflict models considering lighting and traffic conditions.

The primary objective of this study is to explore the effects of the lighting level on nighttime safety of signalized intersections based on conflict models under traffic conditions varying in cycles. Nighttime data were collected from a field study at six signalized intersections in Nanjing, Jiangsu Province in China. Nighttime rear-end conflict models were developed by adopting the generalized linear model (GLM) approach to relate the frequency of rear-end traffic conflicts to lighting level, traffic volume and platoon ratio at the signal cycle level.

Stereoselective synthesis of 2,8-dioxabicyclo[3.3.1]nonane derivatives via a sequential Michael addition/bicyclization reaction.

A highly efficient and stereoselective synthesis of coumarin-, 1,3-cyclohexanedione-, and 1,4-naphthoquinone-fused 2,8-dioxabicyclo[3.3.1]nonanes is described.

[Investigation of canine mesenchymal stem cells differentiation to vascular endothelial cell in vitro].

To induce endothelial cell, canine bone marrow-derived mesenchymal stem cells (MSCs) were separated from bone marrow by density gradient centrifugation. The isolated MSCs were induced to form endothelial-like cell in the presence of vascular endothelial growth factor (VEGF), endothelial growth factor (EGF) and so on. These results showed that the cells uniformly took on a cobblestone morphology under the light microscope, and cell nucleolus was in the middle of the cells.

[Hereditary hemorrhagic telangiectasia caused by mutation in intron 4 of ALK1 gene: analysis of a HTT family].

Objective: To investigate the molecular pathogenesis of hereditary hemorrhagic telangiectasia (HHT).

Methods: Peripheral blood samples were collected from a HTT family, including the proband, female, aged 48, and her mother, elder brother, elder sister, younger brother, and son. HHT gene mutations were identified by PCR-SSCP and DNA sequencing and confirmed by reverse sequencing.