Publications by authors named "Zhexia Fan"

Article Synopsis
  • Researchers are focusing on improving broiler chickens for better meat production through breeding, particularly using the EGR1 gene as a target.
  • EGR1 shows higher expression in chicken breast tissues with lower muscle content and is involved in muscle growth by affecting myoblast behavior.
  • The study identified specific EGR1 gene variations linked to various slaughter traits in the Jiangfeng M3 lineage partridge chickens, helping to enhance breeding strategies.
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Light is a key environmental factor regulating reproduction in avians. However, the mechanism of light intensity regulating ovarian development is still unclear. In this study, 5-week-old (5 wk) partridge broiler breeders were randomly divided into a low-light-intensity group (LL group) and a natural-light-intensity group (NL group) ( = 100).

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Background: Previous studies have demonstrated the role of N6-methyladenosine (mA) RNA methylation in various biological processes, our research is the first to elucidate its specific impact on LCAT mRNA stability and adipogenesis in poultry.

Results: The 6 100-day-old female chickens were categorized into high (n = 3) and low-fat chickens (n = 3) based on their abdominal fat ratios, and their abdominal fat tissues were processed for MeRIP-seq and RNA-seq. An integrated analysis of MeRIP-seq and RNA-seq omics data revealed 16 differentially expressed genes associated with to differential mA modifications.

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Introduction: Excessive fat deposition in chickens can lead to reduced feed utilization and meat quality, resulting in significant economic losses for the broiler industry. Therefore, reducing fat deposition has become an important breeding objective in addition to achieving high broiler weight, growth rate, and feed conversion efficiency. In our previous studies, we observed high expression of Regulators of G Protein Signaling 16 Gene () in high-fat individuals.

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