TaWRKY17 Interacts With TaWRKY44 to Promote Expression of TaDHN7 for Salt Tolerance in Wheat.

Wheat is a crucial food crop, yet its production is continually threatened by abiotic stresses, particularly salt stress. Understanding the molecular mechanisms by which wheat responds to salt stress is essential for developing salt-tolerant varieties. In this study, we investigated the molecular pathway involving the wheat TaDHN7 in response to salt stress.

Identifying Prostatic Utricle Translucent Membrane in Hematospermia Patients Using a Novel Nomogram.

Hematospermia, characterized by blood in the ejaculate, is a common and distressing condition in urology. Identifying the underlying causes, including translucent membranes in the prostatic utricle, is crucial for effective management. Despite advancements in diagnostic techniques, reliable predictive tools are needed to enhance preoperative planning and patient outcomes.

An Oxidative Cleavage-Based Cruciform DNA Nanostructure for Hypochlorous Acid Visualization to Monitor Intestinal Inflammation.

Ulcerative colitis is a persistent inflammatory bowel disease characterized by inflammation and ulceration in the colon and gastrointestinal tract. It was indicated that the generation of hypochlorous acid (HClO) through the enzymatic activity of myeloperoxidase is significantly linked to ulcerative colitis. In this study, by assembling two hairpins (Hpa and Hpb) onto a quadrivalent cruciform DNA nanostructure, a novel HClO-activatable fluorescent probe was developed based on DNA nanomaterials (denoted MHDNA), which is sensitive, economic, simple, and stable.

Antioxidant Carbon Dots Nanozyme Loaded in Thermosensitive in situ Hydrogel System for Efficient Dry Eye Disease Treatment.

Purpose: Dry eye disease (DED) is a multifactorial ocular surface disease with a rising incidence. Therefore, it is urgent to construct a reliable and efficient drug delivery system for DED treatment.

Methods: In this work, we loaded C-dots nanozyme into a thermosensitive in situ gel to create C-dots@Gel, presenting a promising composite ocular drug delivery system to manage DED.

A microcosm evaluation of metal cycling in an urbanized contaminated estuary varying with oxic-hypoxic-anoxic-reoxic transition: Behavior, fluxes, and mechanism.

Water hypoxia and metal pollution are commonly co-existed in urbanized estuaries. This study focuses on the effect of an extended dissolved oxygen (DO) full-life dynamics (86 days) on metal behavior across the sediment-water interface through laboratory microcosms from two typical zones in Pearl River Estuary. Combining our time-series results of concentrations and fluxes, it showed that Co, Ni, and Zn consistently presented a release-precipitation-release trajectory with an oxic-hypoxic-anoxic-reoxic transition, characterized with highly variable behavior in the hypoxic-anoxic hotmoments.

Hierarchical Self-Attention Network for Industrial Data Series Modeling With Different Sampling Rates Between the Input and Output Sequences.

For industrial processes, it is significant to carry out the dynamic modeling of data series for quality prediction. However, there are often different sampling rates between the input and output sequences. For the most traditional data series models, they have to carefully select the labeled sample sequence to build the dynamic prediction model, while the massive unlabeled input sequences between labeled samples are directly discarded.

Genome-wide analysis of the Tritipyrum NAC gene family and the response of TtNAC477 in salt tolerance.

NAC transcription factors are widely distributed in the plant kingdom and play an important role in the response to various abiotic stresses in plant species. Tritipyrum, an octoploid derived from hybridization of Triticum aestivum (AABBDD) and Thinopyrum elongatum (EE), is an important genetic resource for integrating the desirable traits of Th. elongatum into wheat.

A Ratiometric Fluorescent Sensor Based on Chelation-Enhanced Fluorescence of Carbon Dots for Zinc Ion Detection.

Zinc ion, one of the most important transition metal ions in living organisms, plays a crucial role in the homeostasis of the organism. The disorder of zinc is associated with many major diseases. It is highly desirable to develop selective and sensitive methods for the real-time detection of zinc ions.

The impact of community nucleic acid testing on infection in residential compounds during a city-wide lockdown.

The question of whether community nucleic acid testing contributes to an increase in infections within residential compounds has not been definitively answered. Shanghai, one of the largest cities in China, conducted city-wide community testing during its lockdown from late March to May 2022. This situation provided a unique opportunity to examine the effect of community testing on infection rates, as the lockdown largely eliminated confounding factors such as citizen mobility.

How does green digital finance drive the low-carbon energy transition in China?

In the modern world, green digital financing is believed to be an efficient, resilient, and viable source of funding for crisis conditions and to solve the preceding issues in a timely manner. It is a modern tool of financing mainly introduced by the World Bank and the International Monetary Fund. Following the paths, most economies started considering it to solve their national economic issues.

Analysis on the geographical pattern and driving force of traditional villages based on GIS and Geodetector: a case study of Guizhou, China.

Traditional villages have received widespread attention from all walks of life based on important carriers of Chinese rural culture. The mutual superposition of natural and cultural factors may exacerbate the evolution of traditional village geographical patterns. To understand such relationships and effects, factors and degrees influencing traditional villages need to be determined.

Generation of Simulated "Natural" Nanoplastics from Polypropylene Food Packaging as the Experimental Standard.

Current toxicology research on nanoplastics (NPs) generally uses commercial spherical NPs. However, the physicochemical characteristics of commercial NPs are significantly different from those of NPs formed under natural conditions, possibly affecting the validity of the results. In analytical chemistry, a reference sample is selected such that its physicochemical properties are as similar as possible to the target.

Carbon dots with light-responsive oxidase-like activity for colorimetric detection of dopamine and the catalytic mechanism.

Dopamine is one of the most significant neurotransmitters and plays an important role in the management of cognitive functions such as learning, memory, and behavior. The disorder of dopamine is associated with many major mental diseases. It is necessary to develop selective methods for the detection of dopamine.

Polystyrene nanoparticles induced mammalian intestine damage caused by blockage of BNIP3/NIX-mediated mitophagy and gut microbiota alteration.

Nanoplastics possess the capacity for cellular internalization, and consequentially disrupt mitochondrial functionality, precipitating aberrations in energy metabolism. Given this, the potential accumulation of nanoplastics in alimentary sources presents a considerable hazard to the mammalian gastrointestinal system. While mitophagy serves as a cytoprotective mechanism that sustains redox homeostasis through the targeted removal of compromised mitochondria, the regulatory implications of mitophagy in nanoplastic-induced toxicity remain an underexplored domain.

Determination of no observable effect level of nanoplastics on intestinal flora.

The risk of human exposure to nanoplastics (NPs) is increasing due to the incomplete decomposition and accumulation of plastic debris in the environment. Dietary intake is the most common way for human body to ingest NPs. NPs cannot degrade in vivo and will accumulate in multiple tissues, which result in various tissue damages.

Porphyrin Supramolecular Nanoassembly/CN Nanosheet S-Scheme Heterojunctions for Selective Photocatalytic CO Reduction toward CO.

The photocatalytic reduction of CO with HO into valuable chemicals is a sustainable carbon-neutral technology for renewable energy; however, the photocatalytic activity and product selectivity remain challenging. Herein, an S-scheme heterojunction photocatalyst with superior CO photoreduction performance─porous CN (CN) nanosheets anchored with zinc(II) tetra(4-cyanophenyl)porphyrin (ZnTP) nanoassemblies (denoted as ZnTP/CN)─was designed and prepared via a simple self-assembly process. The constructed ZnTP/CN heterojunction had rich accessible active sites, improved CO absorption capacity, and high charge carrier separation efficiency caused by the S-scheme heterojunction.

Genetically encoded gelation redox-responsive collagen-like protein hydrogel for accelerating diabetic wound healing.

Genetically encoded collagen-like protein-based hydrogels have demonstrated remarkable efficacy in promoting the healing process in diabetic patients. However, the current methods for preparing these hydrogels pose significant challenges due to harsh reaction conditions and the reliance on chemical crosslinkers. In this study, we present a genetically encoded approach that allows for the creation of protein hydrogels without the need for chemical additives.

Genome-wide analysis of the AP2/ERF gene family in Tritipyrum and the response of TtERF_B2-50 in salt-tolerance.

The AP2/ERF transcription factor is widely distributed across the plant kingdom and plays a crucial role in various abiotic stress responses in plants. Tritipyrum, an octoploid resulting from an intergeneric cross between Triticum aestivum (AABBDD) and Thinopyrum elongatum (EE), is a valuable source of germplasm for incorporating superior traits of Th. elongatum into T.

Biosensing Intestinal Alkaline Phosphatase by Pregnancy Test Strips Based on Target-Triggered CRISPR-Cas12a Activity to Monitor Intestinal Inflammation.

With an increasing incidence worldwide, inflammatory bowel disease (IBD) is a chronic inflammatory disease affecting the gastrointestinal tract, which impairs the life quality of patients. Therefore, it is of great significance to construct a sensitive, simple, and convenient biosensor to analyze IBD-associated biomarkers for an auxiliary diagnosis of IBD. Intestinal alkaline phosphatase (IAP), expressed by the intestinal epithelium, is an endogenous protein that is thought to play a vital role in maintaining intestinal homeostasis and is considered a potential biomarker for IBD.

Simulation and Characterization of Nanoplastic Dissolution under Different Food Consumption Scenarios.

Understanding of the potential leaching of plastic particles, particularly nanoplastics (NPs), from food packaging is crucial in assessing the safety of the packaging materials. Therefore, the objective of this study was to investigate potential exposure risks by simulating the release of NPs from various plastic packaging materials, including polypropylene (PP), general casting polypropylene (GCPP) or metalized casting polypropylene (MCPP), polyethylene (PE), polyethylene terephthalate (PET), and polyphenylene sulfone (PPSU), under corresponding food consumption scenarios. Surface-enhanced Raman scattering (SERS) and scanning electron microscopy (SEM) were utilized to identify and characterize the NPs leached from plastic packaging.

Brassinosteroids alleviate nanoplastic toxicity in edible plants by activating antioxidant defense systems and suppressing nanoplastic uptake.

As emerging pollutants of global concern, absorbed nanoplastics might have negative impacts on plant development and nutrient uptake, thereby decreasing yields. If nanoplastics are transferred to the edible parts of plants, they may pose a threat to human health when large quantities are ingested. While nanoplastic-induced phytotoxicity is attracting increasing attention, little is known about how to inhibit nanoplastic accumulation in plants and reduce the subsequent adverse effects.

Inhibition of voltage-gated sodium ion channel by corannulene and computational inversion blockage underlying mechanisms.

Corannulene (Cor), a special carbon material, evidenced strong protein binding capacity which regulating lysozyme crystallization and controlling reactive oxygen species (ROS) generation. Ion channel protein play role in regulating ion channel functions to affect physiological functions. However, the interaction between Cor and ion channel protein have not been studied.