It is very important to solve the numerical simulation of fluoropolymer-based reactive materials in the process of engineering design. Although custom development techniques are rapidly being applied to numerical simulation problems of reactive materials, they are inconvenient for engineering designers to implement. This paper presents several simulation methods for fluoropolymer-based reactive materials that can be implemented on commercial software platforms.
View Article and Find Full Text PDFAll-inorganic lead halide perovskite nanocrystals (NCs) have excellent optoelectronic properties and promising applications. Improving the stability of inorganic halide NCs and optimizing their photoluminescence quantum yields (PLQY) has become an urgent task. Constructing core-shell structures is an effective method to improve the environmental stability and PLQY, however, realizing core-shell structured perovskite NCs with good dispersion and multiple perovskites encapsulated within the shell material remains challenging.
View Article and Find Full Text PDFThe protein tyrosine phosphatase 1B (PTP1B) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). Many PTP1B inhibitors have been reported, however, most of them lack high specificity and have adverse effects. Designing effective PTP1B inhibitors requires understanding the molecular mechanism of action between inhibitors and PTP1B.
View Article and Find Full Text PDF2D layered metal halide perovskites (MHPs) are a potential material for fabricating self-powered photodetectors (PDs). Nevertheless, 2D MHPs produced via solution techniques frequently exhibit multiple quantum wells, leading to notable degradation in the device performance. Besides, the wide band gap in 2D perovskites limits their potential for broad-band photodetection.
View Article and Find Full Text PDFPhotoacoustic tomography (PAT) is a powerful imaging modality for visualizing tissue physiology and exogenous contrast agents. However, PAT faces challenges in visualizing deep-seated vascular structures due to light scattering, absorption, and reduced signal intensity with depth. Optical coherence tomography angiography (OCTA) offers high-contrast visualization of vasculature networks, yet its imaging depth is limited to a millimeter scale.
View Article and Find Full Text PDFShiitake mushrooms () are renowned as the "King of mountain treasures" in China due to their abundant nutritional and health-enhancing properties. Intensive chemical investigations of the fruiting bodies and mycelium of Shiitake mushrooms () afforded five new compounds (), named lentinmacrocycles A-C and lentincoumarins A-B, along with fifteen known compounds (). Their structures and absolute configurations were elucidated by extensive spectroscopic analysis, including one-and two-dimensional (1D and 2D) NMR spectroscopy, circular dichroism (CD), and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS).
View Article and Find Full Text PDFOrganophosphate esters (OPEs), increasingly used as alternatives to brominated flame retardants, are ubiquitous in the global aquatic environment. Despite their potential toxicological impact on ecosystems, community-level risk assessments for OPEs in sediments remain scarce. This study investigated OPE occurrences and composition characteristics in the Bohai Sea's sediments and appraised both individual and joint ecological risks posed by characteristic OPE homologs using ten commonly used species sensitivity distribution (SSD) models, integrating acute-to-chronic conversion and phase equilibrium partitioning.
View Article and Find Full Text PDFThis study aimed to investigate taste substances of shrimp heads stored at 20 °C, 4 °C, -3 °C, and - 18 °C, and the correlation between taste substances and 25 key volatile substances. Notably, samples stored at 20 °C showed significant changes in bitter amino acids and hypoxanthine, and quickly deteriorated. Samples stored at 4 °C for 14 d or - 3 °C for 30 d facilitated the development of umami amino acids, sweet amino acids, and IMP.
View Article and Find Full Text PDFCuInS (CIS) quantum dots (QDs) represent an important class of colloidal materials with broad application potential, owing to their low toxicity and unique optical properties. Although coating with a ZnS shell has been identified as a crucial method to enhance optical performance, the occurrence of cation exchange has historically resulted in the unintended formation of Cu-In-Zn-S alloyed QDs, causing detrimental blueshifts in both absorption and photoluminescence (PL) spectral profiles. In this study, we present a facile one-pot synthetic strategy aimed at impeding the cation exchange process and promoting ZnS shell growth on CIS core QDs.
View Article and Find Full Text PDFNon-contact optical temperature measurement can effectively avoid the disadvantages of traditional contact thermometry and thus, become a hot research topic. Herein, a fluorescence intensity ratio (FIR) thermometry using a time-resolved technique based on LaCaZrO:Cr (LCZO) is proposed, with a maximum relative sensitivity (Sr - FIR) of 2.56% K at 473 K and a minimum temperature resolution of 0.
View Article and Find Full Text PDFPhotoacoustic tomography (PAT) and magnetic resonance imaging (MRI) are two advanced imaging techniques widely used in pre-clinical research. PAT has high optical contrast and deep imaging range but poor soft tissue contrast, whereas MRI provides excellent soft tissue information but poor temporal resolution. Despite recent advances in medical image fusion with pre-aligned multimodal data, PAT-MRI image fusion remains challenging due to misaligned images and spatial distortion.
View Article and Find Full Text PDFCylindrical organs, e.g., blood vessels, airways, and intestines, are ubiquitous structures in biomedical optical imaging analysis.
View Article and Find Full Text PDFEndoscopic airway optical coherence tomography (OCT) is a non-invasive and high resolution imaging modality for the diagnosis and analysis of airway-related diseases. During OCT imaging of the upper airway, in order to reliably characterize its 3D structure, there is a need to automatically detect the airway lumen contour, correct rotational distortion and perform 3D airway reconstruction. Based on a long-range endoscopic OCT imaging system equipped with a magnetic tracker, we present a fully automatic framework to reconstruct the 3D upper airway model with correct bending anatomy.
View Article and Find Full Text PDFAlthough Cr as activator for Near infrared (NIR) phosphors has been widely studied, the peaks of Cr emission spectra in most hosts are less than 1000 nm. Nd as an activator in many hosts has a wide distribution of absorption peaks in the Ultraviolet-visible-Near infrared (UV-vis-NIR) band, especially in the 650-900 nm band for effective NIR to NIR Stokes luminescence (F→I, F→I transitions). Therefore, Cr, Nd co-doping to achieve the emission in the NIR II region (1000-1700nm) is very meaningful.
View Article and Find Full Text PDFEthnopharmacological Relevance: Shang-Ke-Huang-Shui lotion (SKHS), an experiential formula based on the theory of traditional Chinese medicine as a hospital preparation, combines Coptidis Rhizoma, Phellodendri Chinensis Cortex, Gardeniae Fructus, Arnebiae Radix, Menthae Haplocalycis Herba and Alumen. While it has acquired positive effects on the treatment of soft tissue injuries, there is no systematic safety assessment in recent studies.
Aim Of The Study: The study aimed to investigate the acute and long-term toxicity in New Zealand White rabbits using topical administration of SKHS.
Photoacoustic tomography (PAT) images contain inherent distortions due to the imaging system and heterogeneous tissue properties. Improving image quality requires the removal of these system distortions. While model-based approaches and data-driven techniques have been proposed for PAT image restoration, achieving accurate and robust image recovery remains challenging.
View Article and Find Full Text PDFFront Med (Lausanne)
June 2023
Background: Second primary colorectal cancer (CRC) is attributed to a crucial component of the CRC population. Still, its treatments remain unclear due to the troublesome conditions originating from multiple primary cancers and the lack of quality evidence. This study aimed to determine that which type of surgical resection is the eligible treatment for second primary CRC among patients with a prior cancer history.
View Article and Find Full Text PDFObjective: To evaluate the expression of tumor stem cell marker CD133 in peripheral blood circulating tumor cells (CTC) and the value of CD133 in prognosis of patients with colorectal cancer (CRC).
Methods: Preoperative/pre-chemotherapy peripheral blood samples of 63 patients with CRC from January 2016 to January 2021 were selected to detect peripheral blood CTC by CanPatrol CTC enrichment technology. Expression of CD133 in different epithelial-mesenchymal transition (EMT) typing CTC was analyzed.
Clin Transl Oncol
December 2023
Purpose: HOX transcribed antisense RNA (HOTAIR) is a long noncoding RNA (LncRNA) that promotes tumor progression. Exosomes are critically involved in cancer progression. The presence of HOTAIR in the circulating exosomes and the roles of exosomal HOTAIR in gastric cancer (GC) remains unknown.
View Article and Find Full Text PDFLead-free double perovskites have emerged as a promising class of materials with potential to be integrated into a wide range of optical and optoelectronic applications. Herein, the first synthesis of 2D Cs AgIn Bi Cl (0 ≤ x ≤ 1) alloyed double perovskite nanoplatelets (NPLs) with well controlled morphology and composition is demonstrated. The obtained NPLs show unique optical properties with the highest photoluminescence quantum yield of 40.
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